Abstract
The organometallic arene ruthenium complexes are rapidly advancing. In particular, the organoruthenium complexes of the type [(η6-arene)Ru(X)(Y)(Z)] have attracted increasing attention for their special structures and properties. This review is focused on the recent developments of [(η6- arene)Ru(X)(Y)(Z)]-typed complexes incorporating various biologically active ligands, which are important in the exploration of novel multi-targeted organometallic anticancer drugs.
Keywords: Anticancer agent, Arene, Biologically active ligands, Ruthenium.
Mini-Reviews in Medicinal Chemistry
Title:Development of Arene Ruthenium Antitumor Complexes
Volume: 16 Issue: 10
Author(s): Wei Su, Zhaofeng Tang and Peiyuan Li
Affiliation:
Keywords: Anticancer agent, Arene, Biologically active ligands, Ruthenium.
Abstract: The organometallic arene ruthenium complexes are rapidly advancing. In particular, the organoruthenium complexes of the type [(η6-arene)Ru(X)(Y)(Z)] have attracted increasing attention for their special structures and properties. This review is focused on the recent developments of [(η6- arene)Ru(X)(Y)(Z)]-typed complexes incorporating various biologically active ligands, which are important in the exploration of novel multi-targeted organometallic anticancer drugs.
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Cite this article as:
Su Wei, Tang Zhaofeng and Li Peiyuan, Development of Arene Ruthenium Antitumor Complexes, Mini-Reviews in Medicinal Chemistry 2016; 16 (10) . https://dx.doi.org/10.2174/138955751610160503003937
DOI https://dx.doi.org/10.2174/138955751610160503003937 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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