Selenium Compounds Biotransformed by Mushrooms: Not Only Dietary Sources, But Also Toxicity Mediators

Title:Selenium Compounds Biotransformed by Mushrooms: Not Only Dietary Sources, But Also Toxicity Mediators

Volume: 13 Issue: 2

Author(s): Olga Tsivileva*Alla Perfileva

Affiliation:

• Institute of Biochemistry and Physiology of Plants and Microorganisms, RAS, 13 Prospekt Entuziastov, Saratov 410049,Russian Federation

Keywords: Selenium, essentiality, bioavailability, supplementation, Se-fortified food, Se-yeast, selenized mycelium, macrobasidiomycetes.

Abstract: Background: The trace element selenium (Se) is essential nutrition mineral. Selenium deficiencies in the human and animal organism are recognized worldwide to be related to a number of pathologies. However, at higher Se concentrations, harmful consequences occur: generation of free radicals, DNA double-strand breaks, and apoptosis in cells. Provided that the recommended dietary intakes are not met, Se-rich foods are to be included in the diet.

Limitation of Se Studies: The disparate opinions on the widely discussed chemopreventive capability of selenium have to be addressed. Of paramount importance is a better understanding of the Se significance to the DNA preservation and cancer. The contradictions found might be related to poor understanding of controversial mechanisms involved in selenium biochemistry. Therefore, a rich area of selenium explorations could be considered as two fields: Se as a dietary component and Se as a toxic agent.

Selenized Fungi: Mushrooms and yeasts have attracted a number of researchers in food and pharmaceuticals. Mushroom-based foods enriched with selenocompounds could be a convenient source of Se to balance the deficiency. Therewith the safety and efficacy factors favor the organic forms of Se.

Conclusion: The consequences of selenium toxicity, bioavailability of selenium content, the importance and possibilities for increasing selenium content of mushroom mycelia, a fate of organoselenium xenobiotics in the basidiomycetes culture are discussed in this review.

Cite this article as:

Tsivileva Olga*, Perfileva Alla, Selenium Compounds Biotransformed by Mushrooms: Not Only Dietary Sources, But Also Toxicity Mediators, Current Nutrition & Food Science 2017; 13 (2) . https://dx.doi.org/10.2174/1573401313666170117144547

DOI https://dx.doi.org/10.2174/1573401313666170117144547	Print ISSN 1573-4013
Publisher Name Bentham Science Publisher	Online ISSN 2212-3881