Abstract
Gallic acid and its derivatives not only exhibit excellent antioxidant, anticarcinogenic, antimutagenic, antimicrobial properties but also provide protection to the cells against oxidative stress. Gallic acid (3, 4, 5-trihydroxybenzoic acid), a low molecular triphenolic compound emerged as an efficient apoptosis inducing agent. The antimicrobial and other biological properties of gallic acid and its derivatives seemed to be linked with the hydrolysis of ester linkage between gallic acid and polyols like tannins hydrolyzed after ripening of many edible fruits. Gallic acid serves a natural defense mechanism against microbial infections and modulation of immune responses. The current review updates us with the diverse roles played by gallic acid, its antioxidant potential, action mechanism and more importantly the diverse array of applications in therapeutic and pharmaceutical areas.
Keywords: Antioxidant, anti-diabetic, anti-tyrosinase, antimicrobial properties, gallic acid, pharmaceutical areas.
Mini-Reviews in Medicinal Chemistry
Title:Probing Gallic Acid for Its Broad Spectrum Applications
Volume: 18 Issue: 15
Author(s): Sneha Choubey, Soniya Goyal, Lesley Rachel Varughese, Vinod Kumar, Anil K. Sharma and Vikas Beniwal*
Affiliation:
- Department of Biotechnology, Maharishi Markandeshwar University, Mullana, Ambala- 133207 (Haryana),India
Keywords: Antioxidant, anti-diabetic, anti-tyrosinase, antimicrobial properties, gallic acid, pharmaceutical areas.
Abstract: Gallic acid and its derivatives not only exhibit excellent antioxidant, anticarcinogenic, antimutagenic, antimicrobial properties but also provide protection to the cells against oxidative stress. Gallic acid (3, 4, 5-trihydroxybenzoic acid), a low molecular triphenolic compound emerged as an efficient apoptosis inducing agent. The antimicrobial and other biological properties of gallic acid and its derivatives seemed to be linked with the hydrolysis of ester linkage between gallic acid and polyols like tannins hydrolyzed after ripening of many edible fruits. Gallic acid serves a natural defense mechanism against microbial infections and modulation of immune responses. The current review updates us with the diverse roles played by gallic acid, its antioxidant potential, action mechanism and more importantly the diverse array of applications in therapeutic and pharmaceutical areas.
Export Options
About this article
Cite this article as:
Choubey Sneha , Goyal Soniya , Varughese Rachel Lesley , Kumar Vinod , Sharma K. Anil and Beniwal Vikas*, Probing Gallic Acid for Its Broad Spectrum Applications, Mini-Reviews in Medicinal Chemistry 2018; 18 (15) . https://dx.doi.org/10.2174/1389557518666180330114010
DOI https://dx.doi.org/10.2174/1389557518666180330114010 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Sentinel Lymph Node Mapping in Early Stage Endometrial Cancer Patients in Low-Resource Settings
Current Women`s Health Reviews Role of Adiponectin in Cervical Cancer
Current Drug Metabolism AIDS Related Viruses, their Association with Leukemia, and Raf Signaling
Current HIV Research Recent Patents on Anti-Cancer Potential of Helenalin
Recent Patents on Anti-Cancer Drug Discovery Nanopotentiation of Propolis for Revocation of Enzyme Imbalance in UVB Induced Cutaneous Toxicity in Murine Model: a Preliminary Study for Chemoprotection of Skin Cancer
Drug Delivery Letters A Systematic Review of Genes Involved in the Inverse Resistance Relationship Between Cisplatin and Paclitaxel Chemotherapy: Role of BRCA1
Current Cancer Drug Targets Synthesis of 99mTc-Nimotuzumab with Tricarbonyl Ion: in vitro and in vivo Studies
Current Radiopharmaceuticals Composite Lymphomas: A Challenging Entity
Current Cancer Therapy Reviews Physiology of Folic Acid in Health and Disease
Current Drug Metabolism B7-H3-targeted Radioimmunotherapy of Human Cancer
Current Medicinal Chemistry Fibroblast Growth Factor Receptor Signaling in Cancer Biology and Treatment
Current Signal Transduction Therapy Design and Synthesis of Arylnaphthalene Lignan Lactone Derivatives as Potent Topoisomerase Inhibitors
Medicinal Chemistry Chemotherapy with si-RNA and Anti-Cancer Drugs
Current Drug Delivery Therapeutic Applications of Crocus sativus L. (Saffron): A Review
The Natural Products Journal Emerging Vascular Risk Factors in Women: Any Differences from Men?
Current Medicinal Chemistry Targeting Mitochondrial Biogenesis to Treat Insulin Resistance
Current Pharmaceutical Design Glycogen Synthase Kinase-3 Beta; A New Target in Pancreatic Cancer?
Current Cancer Drug Targets Preclinical Studies of Alkylureas as Anti-HIV-1 Contraceptive
Current Pharmaceutical Design Berberine Exhibits Antitumor Effects in Human Ovarian Cancer Cells
Anti-Cancer Agents in Medicinal Chemistry Cucurbitacins as Inducers of Cell Death and a Rich Source of Potential Anticancer Compounds
Current Pharmaceutical Design