Abstract
Sesterterpenes form a small group of terpenoids that are mainly present in the marine world although they are also produced by terrestrial organisms such as fungi, and in minor extent higher plants, lichens and insects. Sesterterpenes are diverse and these compounds display significant biological activities such as anti-inflammatory, cytotoxic, anticancer, antimicrobial, antitubercular, and anti-biofilm. This review presents the sesterterpenoid compounds identified from marine sources between 2013 and 2017. Structures are grouped as scalaranes, linear sesterterpenes and other sesterterpenes. Natural sources and reported biological activities are summarized in a table format.
Keywords: Sesterterpenes, scalaranes, linear sesterterpenes norsesterterpenes, biological activity, cytotoxic, antiproliferative, natural products discovery.
Current Organic Chemistry
Title:Marine Sesterterpenes: An Overview
Volume: 22 Issue: 24
Author(s): Patrícia Máximo and Ana Lourenço*
Affiliation:
- LAQV-REQUIMTE, Departamento de Quimica, Faculdade de Ciencias e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Caparica,Portugal
Keywords: Sesterterpenes, scalaranes, linear sesterterpenes norsesterterpenes, biological activity, cytotoxic, antiproliferative, natural products discovery.
Abstract: Sesterterpenes form a small group of terpenoids that are mainly present in the marine world although they are also produced by terrestrial organisms such as fungi, and in minor extent higher plants, lichens and insects. Sesterterpenes are diverse and these compounds display significant biological activities such as anti-inflammatory, cytotoxic, anticancer, antimicrobial, antitubercular, and anti-biofilm. This review presents the sesterterpenoid compounds identified from marine sources between 2013 and 2017. Structures are grouped as scalaranes, linear sesterterpenes and other sesterterpenes. Natural sources and reported biological activities are summarized in a table format.
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Cite this article as:
Máximo Patrícia and Lourenço Ana *, Marine Sesterterpenes: An Overview, Current Organic Chemistry 2018; 22 (24) . https://dx.doi.org/10.2174/1385272822666181029101212
DOI https://dx.doi.org/10.2174/1385272822666181029101212 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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