Abstract
Tetraterpenoids comprise of a large family of C 40 polyene, obtained from plants, fungi and bacteria. Their colouring properties have been employed to use as a natural colorant in the pharmaceutical industries. These exist as an attractive target of research because of their easy availability and plentiful health benefits in cardiovascular diseases, cancer, age related degenerative diseases, macular degeneration, antiatherosclerotic, anti-inflammatory, immunomodulatory properties and in HIV infection, probably due to their antioxidant properties. Formulating carotenoids in a particular dosage form is a big challenge as they possess some limitations like chemical unstability, poor bioavailability, less solubility and quick release. Due to this, numerous nanoencapsulation techniques have been developed till now to maintain their original properties. This review will highlight the phytochemical and pharmacological update on tetraterpenoids and their formulations.
Keywords: Carotenoids, lycopene, carotene, xanthophylls, nano-formulations, tetraterpenoids.
The Natural Products Journal
Title:Phytochemistry and Pharmacological Update on Tetraterpenoids
Volume: 11 Issue: 5
Author(s): Sapna Kumari*, Anju Goyal and Madhukar Garg
Affiliation:
- Chitkara College of Pharmacy, Chitkara University, Punjab,India
Keywords: Carotenoids, lycopene, carotene, xanthophylls, nano-formulations, tetraterpenoids.
Abstract: Tetraterpenoids comprise of a large family of C 40 polyene, obtained from plants, fungi and bacteria. Their colouring properties have been employed to use as a natural colorant in the pharmaceutical industries. These exist as an attractive target of research because of their easy availability and plentiful health benefits in cardiovascular diseases, cancer, age related degenerative diseases, macular degeneration, antiatherosclerotic, anti-inflammatory, immunomodulatory properties and in HIV infection, probably due to their antioxidant properties. Formulating carotenoids in a particular dosage form is a big challenge as they possess some limitations like chemical unstability, poor bioavailability, less solubility and quick release. Due to this, numerous nanoencapsulation techniques have been developed till now to maintain their original properties. This review will highlight the phytochemical and pharmacological update on tetraterpenoids and their formulations.
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Cite this article as:
Kumari Sapna *, Goyal Anju and Garg Madhukar , Phytochemistry and Pharmacological Update on Tetraterpenoids, The Natural Products Journal 2021; 11 (5) . https://dx.doi.org/10.2174/2210315510999200806154609
DOI https://dx.doi.org/10.2174/2210315510999200806154609 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
Call for Papers in Thematic Issues
Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
Biotransformation is the reaction catalyzed by biological catalysts of either isolated enzymes or whole cell cultures of microorganisms. This process has been extensively applied in the conversion of bioactive terpenoids with high regio- and stereospecifity. This process has been also applied in the lead discovery and development. Aspergillus niger has ...read more
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