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Current Molecular Pharmacology

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ISSN (Print): 1874-4672
ISSN (Online): 1874-4702

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Mini-Review Article

Research Progress and Future Development Potential of Oridonin in Pharmacological Activities

Author(s): Shiying Ye, Shaowei Sun, Jiye Cai and Jinhuan Jiang*

Volume 16, Issue 7, 2023

Published on: 02 February, 2023

Article ID: e301122211463 Pages: 16

DOI: 10.2174/1874467216666221130163634

Price: $65

Abstract

In recent years, attention has increasingly focused on herbal medicines and their bioactive components attributed to their multi-target pharmacological activity and low side effects. Oridonin is a natural diterpenoid extracted from the traditional Chinese herb and is one of the main active components of Rabdosia rubescens. Modern pharmacological studies have shown that oridonin has anti-tumor, anti-bacterial, anti-inflammatory, anti-oxidant, cardiovascular protective, immunomodulatory, and other effects. Based on the published literature in recent years, we outline the pharmacological activities of oridonin, aiming to provide a theoretical basis for the design and development of new oridonin-based drugs, as well as to facilitate the process of oridonin for clinical use.

Keywords: Oridonin, pharmacological activities, anti-tumor, anti-inflammatory, anti-bacterial, anti-oxidant.

Graphical Abstract

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