Abstract
There is a growing awareness of the role of oral pathogens in cardiovascular disease. Chronic oral disease such as periodontitis, leads to inflammation and bleeding of the gums. This bleeding provides a viable portal of entry for the bacteria to the circulation. Once in the circulation oral bacteria can interact with circulating platelets. Their ability to support platelet adhesion and induce platelet aggregation are critical steps in the pathogenesis of the infective process. Oral bacteria use multiple mechanisms to interact with, and activate platelets thus contributing to cardiovascular disease. This chapter will review the various mechanisms oral bacteria use to interact with platelets.
Related Journals
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Current Diabetes Reviews
Current Neurovascular Research
Current Respiratory Medicine Reviews
Current Pediatric Reviews
Infectious Disorders - Drug Targets
Current Stem Cell Research & Therapy
Endocrine, Metabolic & Immune Disorders - Drug Targets
Current Alzheimer Research
Current Aging Science
Related Books
Andrology: Current and Future Developments
Male Infertility: An Integrative Manual of Western and Chinese Medicine
Awake Thoracic Surgery
The Anatomical Foundations of Regional Anesthesia and Acute Pain Medicine Macroanatomy Microanatomy Sonoanatomy Functional anatomy
Frontiers in Anti-infective Agents
Frontiers in Anti-infective Agents
Frontiers in Anti-infective Agents
Frontiers in Anti-infective Agents
Frontiers in Anti-infective Agents
Frontiers in Anti-infective Agents