Abstract
We present a comprehensive but not exhaustive review of new trends in drug discovery and targets for cancer and AIDS which begins by highlighting the different historical stages of drug discovery from clinical diagnosis, natural compounds, serendipity and chemotherapy to the present age of modern experimental and computational techniques. The current state of the art of computer-aided drug design and selected recent applications to Cancer and AIDS are discussed. Novel targets and drugs in Cancer and AIDS are analyzed. In conclusion, future perspectives for drug discovery, design and therapeutics in cancer and AIDS are presented.
Keywords: HIV-1, non-nucleoside reverse transcriptase inhibitors (NNRTIs), chemokine co-receptors, anti-VEGF antibody, molecular modeling (MM)
Current Computer-Aided Drug Design
Title: Cancer and Aids: New Trends in Drug Design and Chemotherapy
Volume: 2 Issue: 3
Author(s): Carlton Anthony Taft and Carlos Henrique Tomich de Paula da Silva
Affiliation:
Keywords: HIV-1, non-nucleoside reverse transcriptase inhibitors (NNRTIs), chemokine co-receptors, anti-VEGF antibody, molecular modeling (MM)
Abstract: We present a comprehensive but not exhaustive review of new trends in drug discovery and targets for cancer and AIDS which begins by highlighting the different historical stages of drug discovery from clinical diagnosis, natural compounds, serendipity and chemotherapy to the present age of modern experimental and computational techniques. The current state of the art of computer-aided drug design and selected recent applications to Cancer and AIDS are discussed. Novel targets and drugs in Cancer and AIDS are analyzed. In conclusion, future perspectives for drug discovery, design and therapeutics in cancer and AIDS are presented.
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Cite this article as:
Anthony Taft Carlton and Henrique Tomich de Paula da Silva Carlos, Cancer and Aids: New Trends in Drug Design and Chemotherapy, Current Computer-Aided Drug Design 2006; 2 (3) . https://dx.doi.org/10.2174/157340906778226382
DOI https://dx.doi.org/10.2174/157340906778226382 |
Print ISSN 1573-4099 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6697 |
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