Abstract
Respiratory viral infections account for a substantial proportion of morbidity world wide and contribute notably to the socioeconomic burden of diseases. Amongst the most important viruses identified so far are Rhinoviruses, Influenza A and Respiratory Syncytial Virus. The knowledge base has broadened at the clinical and experimental level in recent years. However, therapeutic options are still limited. This may be partly due to the multiplicity of infectious mechanisms and the complex underlying host/virus interactions. The aim of this article is to give an overview of the different respiratory viruses involved, their major principles of infection and the associated therapeutic targets and to review up-to-date virus-specific clinical trials.
Keywords: Treatment, virus, airway, respiratory, antiviral, influenza, rhinovirus, rsv
Current Medicinal Chemistry
Title: Therapeutic Targets in Respiratory Viral Infections
Volume: 14 Issue: 26
Author(s): Gernot Rohde
Affiliation:
Keywords: Treatment, virus, airway, respiratory, antiviral, influenza, rhinovirus, rsv
Abstract: Respiratory viral infections account for a substantial proportion of morbidity world wide and contribute notably to the socioeconomic burden of diseases. Amongst the most important viruses identified so far are Rhinoviruses, Influenza A and Respiratory Syncytial Virus. The knowledge base has broadened at the clinical and experimental level in recent years. However, therapeutic options are still limited. This may be partly due to the multiplicity of infectious mechanisms and the complex underlying host/virus interactions. The aim of this article is to give an overview of the different respiratory viruses involved, their major principles of infection and the associated therapeutic targets and to review up-to-date virus-specific clinical trials.
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Cite this article as:
Rohde Gernot, Therapeutic Targets in Respiratory Viral Infections, Current Medicinal Chemistry 2007; 14 (26) . https://dx.doi.org/10.2174/092986707782360132
DOI https://dx.doi.org/10.2174/092986707782360132 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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