Abstract
Advances in developmental biology combined with progress in human genetics are helping us decipher how the craniofacial region develops and how the consequences of misdirected development result in malformation. This review describes the molecular etiology of a number of craniofacial developmental anomalies. The more common craniofacial anomalies cleft lip and palate and craniosynostosis, as well as cleidocranial dysplasia, hemifacial microsomia, holoprosencephaly, enlarged parietal foramina, Treacher Collins syndrome and cherubism are discussed.
Keywords: Cleft lip and palate, craniosynostosis, holoprosencephaly, hemifacial microsomia, Treacher Collins syndrome, cleidocranial dysplasia, parietal foramina, cherubism, craniofacial development
Current Molecular Medicine
Title: Craniofacial Anomalies: From Development to Molecular Pathogenesis
Volume: 5 Issue: 7
Author(s): David P.C. Rice
Affiliation:
Keywords: Cleft lip and palate, craniosynostosis, holoprosencephaly, hemifacial microsomia, Treacher Collins syndrome, cleidocranial dysplasia, parietal foramina, cherubism, craniofacial development
Abstract: Advances in developmental biology combined with progress in human genetics are helping us decipher how the craniofacial region develops and how the consequences of misdirected development result in malformation. This review describes the molecular etiology of a number of craniofacial developmental anomalies. The more common craniofacial anomalies cleft lip and palate and craniosynostosis, as well as cleidocranial dysplasia, hemifacial microsomia, holoprosencephaly, enlarged parietal foramina, Treacher Collins syndrome and cherubism are discussed.
Export Options
About this article
Cite this article as:
Rice P.C. David, Craniofacial Anomalies: From Development to Molecular Pathogenesis, Current Molecular Medicine 2005; 5 (7) . https://dx.doi.org/10.2174/156652405774641043
DOI https://dx.doi.org/10.2174/156652405774641043 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Genetics of Atherosclerosis in Murine Models
Current Drug Targets HMG-CoA Reductase Inhibitors: Effects on Chronic Subacute Inflammation and Onset of Atherosclerosis Induced by Dietary Cholesterol
Current Drug Targets - Cardiovascular & Hematological Disorders Drug Therapy for Abdominal Aortic Aneurysms Utilizing Omega-3 Unsaturated Fatty Acids and Their Derivatives
Current Drug Targets Monocytes, Macrophages and Other Inflammatory Mediators of Abdominal Aortic Aneurysm
Current Pharmaceutical Design The Rabbit as an Experimental and Production Animal: From Genomics to Proteomics
Current Protein & Peptide Science Lipoprotein (a) Management: Lifestyle and Hormones
Current Medicinal Chemistry Immunopathology of Brucella Infection
Recent Patents on Anti-Infective Drug Discovery Kawasakis Disease, Acrodynia, and Mercury
Current Medicinal Chemistry Mechanosensitive Channels: Therapeutic Targets in the Myocardium?
Current Pharmaceutical Design Virus-Associated Vasculitides: An Update
Current Immunology Reviews (Discontinued) Sirolimus Eluting Stent: A New Era in Interventional Cardiology?
Current Pharmaceutical Design Role of Transcranial Doppler Ultrasonography in Cerebrovascular Disease
Recent Patents on CNS Drug Discovery (Discontinued) Angiotensin II and Abdominal Aortic Aneurysms: An update
Current Pharmaceutical Design Effect of β-Blockers on Perioperative Myocardial Ischemia in Patients Undergoing Noncardiac Surgery
Current Drug Targets Management of Incidental Findings in the Era of Next-generation Sequencing
Current Genomics Neuroprotective Methodologies of Co-Enzyme Q10 Mediated Brain Hemorrhagic Treatment: Clinical and Pre-Clinical Findings
CNS & Neurological Disorders - Drug Targets Angiotensin II and the Cardiac Complications of Diabetes Mellitus
Current Pharmaceutical Design CT Virtual Intravascular Endoscopy in the Visualization of Coronary Plaques: A Pictorial Essay
Current Medical Imaging Prevention of Immune-mediated Transfusion-related Acute Lung Injury; from Bloodbank to Patient
Current Pharmaceutical Design Implications of microRNAs in the Pathogenesis of Atherosclerosis and Prospects for Therapy
Current Drug Targets