Abstract
This review focuses on the recent developments in study of cationic lipids as carriers for DNA delivery. Emphasis is placed on a class of compounds as exemplifies by their similarity in structures and transfection activities. The technical aspects are also reviewed on how to prepare DNA-lipid complexes and to perform transfection. A brief discussion of the current views on the mechanism of cationic lipid-mediated DNA transfer is intended to provide new prospects for future developments and further improvement of the current systems.
Keywords: cationic lipids, gene delivery, liposomes, nonviral vectors, transfection
Current Medicinal Chemistry
Title: Cationic Transfection Lipids
Volume: 10 Issue: 14
Author(s): Dexi Liu, Tan Ren and Xiang Gao
Affiliation:
Keywords: cationic lipids, gene delivery, liposomes, nonviral vectors, transfection
Abstract: This review focuses on the recent developments in study of cationic lipids as carriers for DNA delivery. Emphasis is placed on a class of compounds as exemplifies by their similarity in structures and transfection activities. The technical aspects are also reviewed on how to prepare DNA-lipid complexes and to perform transfection. A brief discussion of the current views on the mechanism of cationic lipid-mediated DNA transfer is intended to provide new prospects for future developments and further improvement of the current systems.
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Cite this article as:
Liu Dexi, Ren Tan and Gao Xiang, Cationic Transfection Lipids, Current Medicinal Chemistry 2003; 10 (14) . https://dx.doi.org/10.2174/0929867033457386
DOI https://dx.doi.org/10.2174/0929867033457386 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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