Abstract
Gene transfer into stem cells has long been studied as a means by which primitive hematopoietic cells could be characterized and manipulated. While a variety of strategies have been attempted, it still remains relatively difficult to perform direct stem cell analysis. In this review, we examine recent studies using adenovirus-based vectors as a means to achieve high-level gene transfer into primitive hematopoietic cell types.
Keywords: Adenoviral Vectors, Primitive Hematopoietic Cells, Hematopoietic Gene, Fiber Protein, antibody redirection, Hybrid Vectors, Capsid Proteins
Current Gene Therapy
Title: The Use of Adenoviral Vectors for Genetic Manipulation and Analysis of Primitive Hematopoietic Cells
Volume: 1 Issue: 3
Author(s): Craig T. Jordan, Elio F. Vanin and Frank C. Marini
Affiliation:
Keywords: Adenoviral Vectors, Primitive Hematopoietic Cells, Hematopoietic Gene, Fiber Protein, antibody redirection, Hybrid Vectors, Capsid Proteins
Abstract: Gene transfer into stem cells has long been studied as a means by which primitive hematopoietic cells could be characterized and manipulated. While a variety of strategies have been attempted, it still remains relatively difficult to perform direct stem cell analysis. In this review, we examine recent studies using adenovirus-based vectors as a means to achieve high-level gene transfer into primitive hematopoietic cell types.
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Cite this article as:
Jordan T. Craig, Vanin F. Elio and Marini C. Frank, The Use of Adenoviral Vectors for Genetic Manipulation and Analysis of Primitive Hematopoietic Cells, Current Gene Therapy 2001; 1 (3) . https://dx.doi.org/10.2174/1566523013348535
DOI https://dx.doi.org/10.2174/1566523013348535 |
Print ISSN 1566-5232 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5631 |
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