Abstract
A number of new nanotechnology-based Chinese herb drugs have been developed that have efficient biopharmaceutical properties and desirable target characteristics. This offers several alternatives for medical applications. Nanoparticles of Chinese herb drugs possess many benefits, such as improving component solubility, enhancement of bioavailability, increasing absorbency of the organism, reducing medicinal herb doses, and achieving steady-state therapeutic levels of drugs over an extended period compared with traditional Chinese herb drug preparations. There are two basic techniques, ‘bottom up’ or ‘top down’, to prepare Chinese herb nanoparticles. Furthermore, specific surface modifications and new design strategies of Chinese herb drug nanoparticles are created to profit clinical applications. This review presents recent advances in nanotechnology-based Chinese herb drugs.
Keywords: Nanotechnology, Chinese herb drug, Drug carrier, Nanoparticles, Target
Current Drug Metabolism
Title: Advantages of Nanotechnology- Based Chinese Herb Drugs on Biological Activities
Volume: 10 Issue: 8
Author(s): Sherry Huang and Walter H. Chang
Affiliation:
Keywords: Nanotechnology, Chinese herb drug, Drug carrier, Nanoparticles, Target
Abstract: A number of new nanotechnology-based Chinese herb drugs have been developed that have efficient biopharmaceutical properties and desirable target characteristics. This offers several alternatives for medical applications. Nanoparticles of Chinese herb drugs possess many benefits, such as improving component solubility, enhancement of bioavailability, increasing absorbency of the organism, reducing medicinal herb doses, and achieving steady-state therapeutic levels of drugs over an extended period compared with traditional Chinese herb drug preparations. There are two basic techniques, ‘bottom up’ or ‘top down’, to prepare Chinese herb nanoparticles. Furthermore, specific surface modifications and new design strategies of Chinese herb drug nanoparticles are created to profit clinical applications. This review presents recent advances in nanotechnology-based Chinese herb drugs.
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Cite this article as:
Huang Sherry and Chang H. Walter, Advantages of Nanotechnology- Based Chinese Herb Drugs on Biological Activities, Current Drug Metabolism 2009; 10 (8) . https://dx.doi.org/10.2174/138920009790274603
DOI https://dx.doi.org/10.2174/138920009790274603 |
Print ISSN 1389-2002 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5453 |
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