Abstract
The combination of diabetes mellitus and coronary artery disease (CAD) constitutes an aggressive disease characterized biologically by chronic inflammatory, proliferative and pro-thrombotic situation. In the “diabetic patient” the increased frequency and gravity of simultaneous myocardial infarction and the deterioration of congestive heart failure contribute to the inevitable unfavourable final result. Diabetes accelerates the natural course of atherosclerosis and involves a great number of coronary vessels with more diffuse atherosclerotic lesions. Moreover, the risks of plaque ulceration and thrombosis have been shown to be considerably higher in diabetic patients. The treatment should be also aggressive and be based on the combined treatment of CAD and the effective regulation of glucose levels. The decision of revascularization in the diabetic patient should be posed relatively earlier. The surgical choice of revascularization seems to be advantageous over the interventional, with better early and late results.
Keywords: Coronary artery disease, Diabetes mellitus, Coronary artery bypass grafting, Percutaneous transluminal coronary angioplasty, Myocardial infarction, Revascularization, percutaneous transluminal, Surgical revascularization, prothrombotic situation, lipoproteins, manifestations, triglyceride-rich, triggering mechanisms, Plaque-angiogenesis, catabolism, CABG surgery, Abciximab, ischemia, SPECT, AWESOME, worsening symptoms, BASKET-LATE, MACE, perioperatively
Current Diabetes Reviews
Title: Surgical or Interventional Revascularization in Diabetic Patients with Coronary Artery Disease?
Volume: 6 Issue: 6
Author(s): E. Apostolakis, I. Koniari, D. Velissaris and Efstratios N. Koletsis
Affiliation:
Keywords: Coronary artery disease, Diabetes mellitus, Coronary artery bypass grafting, Percutaneous transluminal coronary angioplasty, Myocardial infarction, Revascularization, percutaneous transluminal, Surgical revascularization, prothrombotic situation, lipoproteins, manifestations, triglyceride-rich, triggering mechanisms, Plaque-angiogenesis, catabolism, CABG surgery, Abciximab, ischemia, SPECT, AWESOME, worsening symptoms, BASKET-LATE, MACE, perioperatively
Abstract: The combination of diabetes mellitus and coronary artery disease (CAD) constitutes an aggressive disease characterized biologically by chronic inflammatory, proliferative and pro-thrombotic situation. In the “diabetic patient” the increased frequency and gravity of simultaneous myocardial infarction and the deterioration of congestive heart failure contribute to the inevitable unfavourable final result. Diabetes accelerates the natural course of atherosclerosis and involves a great number of coronary vessels with more diffuse atherosclerotic lesions. Moreover, the risks of plaque ulceration and thrombosis have been shown to be considerably higher in diabetic patients. The treatment should be also aggressive and be based on the combined treatment of CAD and the effective regulation of glucose levels. The decision of revascularization in the diabetic patient should be posed relatively earlier. The surgical choice of revascularization seems to be advantageous over the interventional, with better early and late results.
Export Options
About this article
Cite this article as:
Apostolakis E., Koniari I., Velissaris D. and N. Koletsis Efstratios, Surgical or Interventional Revascularization in Diabetic Patients with Coronary Artery Disease?, Current Diabetes Reviews 2010; 6 (6) . https://dx.doi.org/10.2174/157339910793499100
DOI https://dx.doi.org/10.2174/157339910793499100 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Mechanisms of the Beneficial Actions of Ischemic Preconditioning on Subcellular Remodeling in Ischemic-Reperfused Heart
Current Cardiology Reviews Evaluating the Safety and Tolerability of Azilsartan Medoxomil Alone or in Combination With Chlorthalidone in the Management of Hypertension: A Systematic Review
Current Hypertension Reviews Chemical Connexin Impairment in the Developing Gonad Associated with Offspring Infertility
Current Medicinal Chemistry Prediction Models and Scores in Adult Congenital Heart Disease
Current Pharmaceutical Design Chymase Inhibitors
Current Pharmaceutical Design Crystallization and Preliminary X-Ray Analysis of the Highly Thermostable Sweet Protein Mabinlin II
Protein & Peptide Letters TGFb and its Smad Connection to Cancer
Current Genomics Tumor Angiogenesis: A Potential Target In Cancer Control by Phytochemicals
Current Cancer Drug Targets Polymer-Drug Nanoconjugate – An Innovative Nanomedicine: Challenges and Recent Advancements in Rational Formulation Design for Effective Delivery of Poorly Soluble Drugs
Pharmaceutical Nanotechnology From Amino Acids to Proteins as Targets for Metal-based Drugs
Current Drug Metabolism Anti-Angiogenic Effects of Resveratrol on Cerebral Angiogenesis
Current Neurovascular Research Advanced Glycation: How are we Progressing to Combat this Web of Sugar Anomalies in Diabetic Nephropathy
Current Pharmaceutical Design Three Dimensional Echocardiography: Recent Trends in Segmen tation Methods
Current Medical Imaging Inotropic Therapies in Asphyxiated Neonates: The Clinical and Laboratory Facts
Current Pediatric Reviews Editorial: Herbal Medicine on High Impact Disease: The Current Progress and Application
Current Pharmaceutical Design Neuroimmune Activation in Chronic Heart Failure
Endocrine, Metabolic & Immune Disorders - Drug Targets Therapeutic Potential of Neuregulin in Cardiovascular System: Can we Ignore the Effects of Neuregulin on Electrophysiology?
Mini-Reviews in Medicinal Chemistry Cellular and Pharmacological Targets to Induce Coronary Arteriogenesis
Current Cardiology Reviews Mechanisms for Progenitor Cell-Mediated Repair for Ischemic Heart Injury
Current Stem Cell Research & Therapy Impact of Polypharmacy on Adherence to Evidence-Based Medication in Patients who Underwent Percutaneous Coronary Intervention
Current Vascular Pharmacology