Abstract
Cardiovascular disease is the main cause of death in the United States. Although it is recognized that moderate intensity long-term exercise can decrease the chances of dying from cardiovascular disease by favorably modifying risk factors such as hypertension, obesity, hyperlipidemia, and insulin resistance, physical activity also enhances longevity by mechanisms independent of these risk factors. This review briefly summarizes what is known about the inflammatory nature of atherosclerosis and how long-term aerobic exercise can reduce the atherogenic activity of endothelial cells, blood mononuclear cells, and adipose tissue.
Keywords: Exercise, cardiovascular disease, cardiorespiratory fitness, atherogenesis, vascular endothelial cells, peripheral blood mononuclear cells, adipose tissue, inflammation, cell-mediated immunity, hypertension, obesity, hyperlipidemia, insulin resistance, immunopathogenesis, vascular endothelial cells (VEC), Chlamydia pneumoniae, cytomegalovirus, heat shock protein 60 (Hsp 60), chemokines, prostacyclin PGI2, adrenomedullin, granulopoiesis, immunogens, metalloproteinases, phosphorylation, eNOS protein, adipocytes, lymphocytes, fibroblasts, adipokines, monocytes
Cardiovascular & Hematological Disorders-Drug Targets
Title: Exercise and Cardiovascular Disease
Volume: 10 Issue: 4
Author(s): J. Kelly Smith
Affiliation:
Keywords: Exercise, cardiovascular disease, cardiorespiratory fitness, atherogenesis, vascular endothelial cells, peripheral blood mononuclear cells, adipose tissue, inflammation, cell-mediated immunity, hypertension, obesity, hyperlipidemia, insulin resistance, immunopathogenesis, vascular endothelial cells (VEC), Chlamydia pneumoniae, cytomegalovirus, heat shock protein 60 (Hsp 60), chemokines, prostacyclin PGI2, adrenomedullin, granulopoiesis, immunogens, metalloproteinases, phosphorylation, eNOS protein, adipocytes, lymphocytes, fibroblasts, adipokines, monocytes
Abstract: Cardiovascular disease is the main cause of death in the United States. Although it is recognized that moderate intensity long-term exercise can decrease the chances of dying from cardiovascular disease by favorably modifying risk factors such as hypertension, obesity, hyperlipidemia, and insulin resistance, physical activity also enhances longevity by mechanisms independent of these risk factors. This review briefly summarizes what is known about the inflammatory nature of atherosclerosis and how long-term aerobic exercise can reduce the atherogenic activity of endothelial cells, blood mononuclear cells, and adipose tissue.
Export Options
About this article
Cite this article as:
Kelly Smith J., Exercise and Cardiovascular Disease, Cardiovascular & Hematological Disorders-Drug Targets 2010; 10 (4) . https://dx.doi.org/10.2174/187152910793743823
DOI https://dx.doi.org/10.2174/187152910793743823 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Functional Food with Some Health Benefits, So Called Superfood: A Review
Current Nutrition & Food Science The Roles of Vitamin D and Its Analogs in Inflammatory Diseases
Current Topics in Medicinal Chemistry Prostacyclin Synthase Gene: Implication and Prevention of Cardiovascular Disease
Vascular Disease Prevention (Discontinued) Past, Present and Future of Nutrigenomics and its Influence on Drug Development
Current Drug Discovery Technologies COX-2 and the Kidneys
Current Pharmaceutical Design The Antiplatelet Drug Target in Atherosclerotic Diseases
Cardiovascular & Hematological Disorders-Drug Targets A Novel Method Aimed at Counteracting the Side Effects Caused by Prostaglandin E<sub>2</sub> Deficiency During Non-Steroidal Anti-Inflammatory Drug Therapy
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Bayes Syndrome and Imaging Techniques
Current Cardiology Reviews Editorial from Guest Editor: Current Management of Sleep Apnea and Comorbidities
Current Respiratory Medicine Reviews Novel Therapeutic Approaches Based on the Targeting of Microenvironment-Derived Survival Pathways in Human Cancer: Experimental Models and Translational Issues
Current Pharmaceutical Design Novel Agents Targeting Nitric Oxide
Current Vascular Pharmacology Development of Nitric Oxide Donors for the Treatment of Cardiovascular Diseases
Cardiovascular & Hematological Agents in Medicinal Chemistry From Molecular Footprints of Disease to New Therapeutic Interventions in Diabetic Nephropathy: A Detective Story
Current Drug Targets - Immune, Endocrine & Metabolic Disorders Outcome Prediction after Non-aneurysmal Non-traumatic Subarachnoid Hemorrhage
Current Neurovascular Research Three Musketeers for Lowering Cholesterol: Statins, Ezetimibe and Evolocumab
Current Medicinal Chemistry Collateral Circulation in Chronic Total Occlusions – an interventional perspective
Current Cardiology Reviews Centrality Measures in Biological Networks
Current Bioinformatics Tryptamine Induces Axonopathy and Mitochondriopathy Mimicking Neurodegenerative Diseases via Tryptophanyl-tRNA Deficiency
Current Alzheimer Research Alerting Reaction in Office Blood Pressure and Target Organ Damage: An Innocent Phenomenon?
Current Hypertension Reviews Sorafenib Decreases Extrahepatic Collaterals in Hepatocellular Carcinoma: Implication of the Synergistic Effect of Sorafenib and Transcatheter Chemoembolization
Current Medical Imaging