Abstract
Coronary artery disease (CAD) is the main cause of death and remains a major health problem worldwide. Myocardial perfu-sion imaging is a well established noninvasive method for assessing CAD. This review summarizes the development of various ra-diotracers for myocardial perfusion imaging, including single photon emission computed tomography (SPECT) perfusion imaging agents and positron emission tomography (PET) perfusion imaging agents and introduces novel basic research data related to this area. In addi-tion, the current state of the art in myocardial perfusion imaging agents and the future direction are discussed in this review.
Keywords: Radiotracers, myocardial, perfusion, imaging, nuclear medicine, Coronary artery disease (CAD), single photon emission computed tomography (SPECT), positron emission tomography (PET), infarction
Current Pharmaceutical Design
Title: Development of Radiolabeled Compounds for Myocardial Perfusion Imaging
Volume: 18 Issue: 8
Author(s): Xiao Lin, Junbo Zhang, Xuebin Wang, Zhigang Tang, Xianzhong Zhang and Jie Lu
Affiliation:
Keywords: Radiotracers, myocardial, perfusion, imaging, nuclear medicine, Coronary artery disease (CAD), single photon emission computed tomography (SPECT), positron emission tomography (PET), infarction
Abstract: Coronary artery disease (CAD) is the main cause of death and remains a major health problem worldwide. Myocardial perfu-sion imaging is a well established noninvasive method for assessing CAD. This review summarizes the development of various ra-diotracers for myocardial perfusion imaging, including single photon emission computed tomography (SPECT) perfusion imaging agents and positron emission tomography (PET) perfusion imaging agents and introduces novel basic research data related to this area. In addi-tion, the current state of the art in myocardial perfusion imaging agents and the future direction are discussed in this review.
Export Options
About this article
Cite this article as:
Lin Xiao, Zhang Junbo, Wang Xuebin, Tang Zhigang, Zhang Xianzhong and Lu Jie, Development of Radiolabeled Compounds for Myocardial Perfusion Imaging, Current Pharmaceutical Design 2012; 18 (8) . https://dx.doi.org/10.2174/138161212799315876
DOI https://dx.doi.org/10.2174/138161212799315876 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
Call for Papers in Thematic Issues
"Tuberculosis Prevention, Diagnosis and Drug Discovery"
The Nobel Prize-winning discoveries of Mycobacterium tuberculosis and streptomycin have enabled an appropriate diagnosis and an effective treatment of tuberculosis (TB). Since then, many newer diagnosis methods and drugs have been saving millions of lives. Despite advances in the past, TB is still a leading cause of infectious disease mortality ...read more
Current Pharmaceutical challenges in the treatment and diagnosis of neurological dysfunctions
Neurological dysfunctions (MND, ALS, MS, PD, AD, HD, ALS, Autism, OCD etc..) present significant challenges in both diagnosis and treatment, often necessitating innovative approaches and therapeutic interventions. This thematic issue aims to explore the current pharmaceutical landscape surrounding neurological disorders, shedding light on the challenges faced by researchers, clinicians, and ...read more
Emerging and re-emerging diseases
Faced with a possible endemic situation of COVID-19, the world has experienced two important phenomena, the emergence of new infectious diseases and/or the resurgence of previously eradicated infectious diseases. Furthermore, the geographic distribution of such diseases has also undergone changes. This context, in turn, may have a strong relationship with ...read more
Melanoma and Non-Melanoma Skin Cancer Treatment: Standard of Care and Recent Advances
In this thematic issue, we aim to provide a standard of care of the diagnosis and treatment of melanoma and non-melanoma skin cancer. The editor will invite authors from different countries who will write review articles of melanoma and non-melanoma skin cancers. The Diagnosis, Staging, Surgical Treatment, Non-Surgical Treatment all ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
A Novel Systemic Indicator of Periodontal Tissue Damage: Ischemia Modified Albumin
Combinatorial Chemistry & High Throughput Screening The Therapeutic Potential of Neural Stem Cells in Cerebral Ischemia
Current Signal Transduction Therapy Ca2+ Signalling in Damaged Endothelium and Arterial Remodelling: Do Connexin Hemichannels Provide a Suitable Target to Prevent In-stent Restenosis?
Current Drug Therapy Impaired Expression and Function of Signaling Pathway Enzymes by Anthocyanins: Role on Cancer Prevention and Progression
Current Enzyme Inhibition Prevention of Sudden Cardiac Death in Hemodialysis Patients
Cardiovascular & Hematological Disorders-Drug Targets Aldehyde Dehydrogenase-2 Roles in Ischemic Cardiovascular Disease
Current Drug Targets Biomarkers for Diagnosing and Staging of Fabry Disease
Current Medicinal Chemistry Evaluation of Cardiac Scan in Diagnosing Coronary-artery Disease
Current Medical Imaging Leptin, Ciliary Neurotrophic Factor, Leukemia Inhibitory Factor and Interleukin- 6: Class-I Cytokines Involved in the Neuroendocrine Regulation of the Reproductive Function
Current Protein & Peptide Science α2-Antiplasmin on Cardiovascular Diseases
Current Pharmaceutical Design Nitroimidazole Radiopharmaceuticals in Bioimaging: Part I: Synthesis and Imaging Applications
Current Radiopharmaceuticals Regulatory Role of Chinese Herbal Medicine in Regulated Neuronal Death
CNS & Neurological Disorders - Drug Targets Can microRNAs be Biomarkers or Targets for Therapy of Ischemic Coronary Artery Disease in Metabolic Syndrome?
Current Drug Targets Inotropic Therapies in Asphyxiated Neonates: The Clinical and Laboratory Facts
Current Pediatric Reviews Directions for Enhancement of the Therapeutic Efficacy of Mesenchymal Stem Cells in Different Neurodegenerative and Cardiovascular Diseases: Current Status and Future Perspectives
Current Stem Cell Research & Therapy Cytomegalovirus Infections in Non-Immunocompromised and Immunocompromised Patients in the Intensive Care Unit
Infectious Disorders - Drug Targets Inhibition of Human Serine Racemase, an Emerging Target for Medicinal Chemistry
Current Drug Targets Comprehensive Review on Custodiol-N (HTK-N) and its Molecular Side of Action for Organ Preservation
Current Pharmaceutical Biotechnology Clinical and Pre-clinical Applications of the Transcendental Meditation Program® in the Prevention and Treatment of Essential Hypertension and Cardiovascular Disease in Youth and Adults
Current Hypertension Reviews Cell-Penetrating Peptide Technology to Deliver Chaperones and Associated Factors in Diseases and Basic Research
Current Pharmaceutical Biotechnology