Abstract
Adenosine-to-Inosine RNA editing introduces changes in RNA transcripts via a post-transcriptional mechanism, the hydrolytic deamination of adenosine (A) to inosine (I) which is interpreted as guanosine by cellular machineries. Adenosine deaminases that act on RNA (ADAR) enzymes catalyze editing in double-stranded (ds) RNA substrates.
Keywords: Adenosine, inosine, RNA, editing, drosophila, ion channel, convergence
Mini-Reviews in Medicinal Chemistry
Title: Adenosine-to-Inosine RNA Editing: Perspectives and Predictions
Volume: 6 Issue: 11
Author(s): Barry Hoopengardner
Affiliation:
Keywords: Adenosine, inosine, RNA, editing, drosophila, ion channel, convergence
Abstract: Adenosine-to-Inosine RNA editing introduces changes in RNA transcripts via a post-transcriptional mechanism, the hydrolytic deamination of adenosine (A) to inosine (I) which is interpreted as guanosine by cellular machineries. Adenosine deaminases that act on RNA (ADAR) enzymes catalyze editing in double-stranded (ds) RNA substrates.
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Cite this article as:
Hoopengardner Barry, Adenosine-to-Inosine RNA Editing: Perspectives and Predictions, Mini-Reviews in Medicinal Chemistry 2006; 6 (11) . https://dx.doi.org/10.2174/138955706778742812
DOI https://dx.doi.org/10.2174/138955706778742812 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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