Abstract
The isolation and preparation ten years ago of the fullerenes in bulk quantities, sparked off a truly remarkable interdisciplinary research activity, encompassing diverse fields of chemistry, physics, materials science and medicinal chemistry. Pharmaceutical and biological studies have revealed that fullerene-based compounds exhibit various types of biological activity either in vitro or in vivo and are discussed in this review.
Keywords: Fullerenes, UV-Visible absorption, Photodynamic Therapy, Enzymatic Inhibition, Cell signaling, Apoptosis, Neuroprotective antioxidants, Endohedral Metallofullerenes, MRI contrast agents
Mini-Reviews in Medicinal Chemistry
Title: Fullerenes in Medicinal Chemistry and their Biological Applications
Volume: 1 Issue: 4
Author(s): N. Tagmatarchis and H. Shinohara
Affiliation:
Keywords: Fullerenes, UV-Visible absorption, Photodynamic Therapy, Enzymatic Inhibition, Cell signaling, Apoptosis, Neuroprotective antioxidants, Endohedral Metallofullerenes, MRI contrast agents
Abstract: The isolation and preparation ten years ago of the fullerenes in bulk quantities, sparked off a truly remarkable interdisciplinary research activity, encompassing diverse fields of chemistry, physics, materials science and medicinal chemistry. Pharmaceutical and biological studies have revealed that fullerene-based compounds exhibit various types of biological activity either in vitro or in vivo and are discussed in this review.
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Cite this article as:
Tagmatarchis N. and Shinohara H., Fullerenes in Medicinal Chemistry and their Biological Applications, Mini-Reviews in Medicinal Chemistry 2001; 1 (4) . https://dx.doi.org/10.2174/1389557013406684
DOI https://dx.doi.org/10.2174/1389557013406684 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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