Abstract
Alzheimer disease treatment has yet to yield a successful therapy that addresses the source of the damage found in brains. Of the varied proposed theories of AD etiology, reactive oxygen species (ROS) generation is cited as a common factor. Efforts to reduce the pathology associated with ROS via antioxidants therefore offer new hope to patients suffering from this devastative disease.
Keywords: Antioxidant, calorie restriction, estrogen, free radical, glutathione, oxidation, oxidative stress, therapy
Mini-Reviews in Medicinal Chemistry
Title: Antioxidant Therapy in Alzheimers Disease: Theory and Practice
Volume: 8 Issue: 13
Author(s): Gjumrakch Aliev, Mark E. Obrenovich, V. Prakash Reddy, Justin C. Shenk, Paula I. Moreira, Akihiko Nunomura, Xiongwei Zhu, Mark A. Smith and George Perry
Affiliation:
Keywords: Antioxidant, calorie restriction, estrogen, free radical, glutathione, oxidation, oxidative stress, therapy
Abstract: Alzheimer disease treatment has yet to yield a successful therapy that addresses the source of the damage found in brains. Of the varied proposed theories of AD etiology, reactive oxygen species (ROS) generation is cited as a common factor. Efforts to reduce the pathology associated with ROS via antioxidants therefore offer new hope to patients suffering from this devastative disease.
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Cite this article as:
Aliev Gjumrakch, Obrenovich E. Mark, Reddy Prakash V., Shenk C. Justin, Moreira I. Paula, Nunomura Akihiko, Zhu Xiongwei, Smith A. Mark and Perry George, Antioxidant Therapy in Alzheimers Disease: Theory and Practice, Mini-Reviews in Medicinal Chemistry 2008; 8 (13) . https://dx.doi.org/10.2174/138955708786369582
DOI https://dx.doi.org/10.2174/138955708786369582 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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