Brown Recluse Spider Venom: Proteomic Analysis and Proposal of a Putative Mechanism of Action

Title: Brown Recluse Spider Venom: Proteomic Analysis and Proposal of a Putative Mechanism of Action

Volume: 16 Issue: 8

Author(s): Lucilene D. dos Santos, Nathalia B. Dias, Jose Roberto, A. S. Pinto and Mario S. Palma

Affiliation:

Keywords: Proteomic analysis, spider venom, MudPIT, mass spectrometry, mechanism of action

Abstract: Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures.

Cite this article as:

dos Santos D. Lucilene, Dias B. Nathalia, Roberto Jose, Pinto S. A. and Palma S. Mario, Brown Recluse Spider Venom: Proteomic Analysis and Proposal of a Putative Mechanism of Action, Protein & Peptide Letters 2009; 16 (8) . https://dx.doi.org/10.2174/092986609788923383