Abstract
The azuki bean (Vigna angularis) has been one of the most important and traditional crops of East Asia, where it has long been cultivated. In Japan, the azuki bean is the second-most important legume after soybeans, and it is commonly used as an essential ingredient, e.g., seki-han, a festive rice dish and an, a sweetened bean paste. Azuki beans (V. angularis) have been known to contain proanthocyanidins, a group of polyphenolic bioflavonoids with remarkable radical-scavenging activities. However, little research has provided detailed discussion of the beneficial effects and physiological functions of azuki beans involved in human body. Based on our findings, the authors provide here evidence that azuki bean (V. angularis) extract — including the molecules therein, such as proanthocyanidins and/or dietary fibers — may play a role in suppressing increases of oxidative stress and macrophage infiltration in the kidneys of animal models with hypertension and hyperglycemia. Moreover, azuki bean (V. angularis) extract may affect the vascular and renal expressions of endothelial nitric oxide synthase, which contribute to nitric oxide production. This review aims to summarize findings concerning the beneficial and interesting effects of azuki beans, especially the physiological functions of azuki bean (V. angularis) extract in treating inflammation, hypertension, and diabetic nephropathy.
Keywords: Azuki bean (Vigna angularis), polyphenols, anti-oxidant properties, inflammation, hypertension, diabetic nephropathy
Current Nutrition & Food Science
Title: Beneficial Effects of Azuki Bean (Vigna angularis) Extract: Anti-Oxidant, Anti-Hypertension, and Treatment for Renal Damage
Volume: 5 Issue: 3
Author(s): Shin Sato, Yuuka Mukai and Jyoji Yamate
Affiliation:
Keywords: Azuki bean (Vigna angularis), polyphenols, anti-oxidant properties, inflammation, hypertension, diabetic nephropathy
Abstract: The azuki bean (Vigna angularis) has been one of the most important and traditional crops of East Asia, where it has long been cultivated. In Japan, the azuki bean is the second-most important legume after soybeans, and it is commonly used as an essential ingredient, e.g., seki-han, a festive rice dish and an, a sweetened bean paste. Azuki beans (V. angularis) have been known to contain proanthocyanidins, a group of polyphenolic bioflavonoids with remarkable radical-scavenging activities. However, little research has provided detailed discussion of the beneficial effects and physiological functions of azuki beans involved in human body. Based on our findings, the authors provide here evidence that azuki bean (V. angularis) extract — including the molecules therein, such as proanthocyanidins and/or dietary fibers — may play a role in suppressing increases of oxidative stress and macrophage infiltration in the kidneys of animal models with hypertension and hyperglycemia. Moreover, azuki bean (V. angularis) extract may affect the vascular and renal expressions of endothelial nitric oxide synthase, which contribute to nitric oxide production. This review aims to summarize findings concerning the beneficial and interesting effects of azuki beans, especially the physiological functions of azuki bean (V. angularis) extract in treating inflammation, hypertension, and diabetic nephropathy.
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Cite this article as:
Sato Shin, Mukai Yuuka and Yamate Jyoji, Beneficial Effects of Azuki Bean (Vigna angularis) Extract: Anti-Oxidant, Anti-Hypertension, and Treatment for Renal Damage, Current Nutrition & Food Science 2009; 5 (3) . https://dx.doi.org/10.2174/157340109789007117
DOI https://dx.doi.org/10.2174/157340109789007117 |
Print ISSN 1573-4013 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3881 |
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