Abstract
Adipose tissue is an attractive source of multipotent adult stem cells due to its wide-spread availability, accessibility, and ease of harvest. Adipose-derived stem cells (ASCs), the adherent stromal cell population present within adipose tissue, are easily expanded in culture, able to differentiate along multiple cell-lineage pathways, and have been shown to provide therapeutic benefit in models of injury and disease through immunomodulation, structural integation, and/or trophic support. Recent developments in the characterization of ASCs, specifically their isolation, gene and protein expression, differentiation, and expansion, are reviewed in this article.
Keywords: Characterization, isolation, donor variability, expansion, adipose-derived stem cell, stromal cell
Current Stem Cell Research & Therapy
Title: Characterization of Adipose-Derived Stem Cells: An Update
Volume: 5 Issue: 2
Author(s): Alexander M. Bailey, Sahil Kapur and Adam J. Katz
Affiliation:
Keywords: Characterization, isolation, donor variability, expansion, adipose-derived stem cell, stromal cell
Abstract: Adipose tissue is an attractive source of multipotent adult stem cells due to its wide-spread availability, accessibility, and ease of harvest. Adipose-derived stem cells (ASCs), the adherent stromal cell population present within adipose tissue, are easily expanded in culture, able to differentiate along multiple cell-lineage pathways, and have been shown to provide therapeutic benefit in models of injury and disease through immunomodulation, structural integation, and/or trophic support. Recent developments in the characterization of ASCs, specifically their isolation, gene and protein expression, differentiation, and expansion, are reviewed in this article.
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Cite this article as:
M. Bailey Alexander, Kapur Sahil and J. Katz Adam, Characterization of Adipose-Derived Stem Cells: An Update, Current Stem Cell Research & Therapy 2010; 5 (2) . https://dx.doi.org/10.2174/157488810791268555
DOI https://dx.doi.org/10.2174/157488810791268555 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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