Abstract
Nanotechnology is playing major role in modern therapeutics for effective delivery of drugs to the troublesome target sites. Human eye presents various physiological and anatomical constraints limiting the absorption of therapeutic agent delivered on its surface by conventional ophthalmic dosage forms. Dosage form variables- like particle size, charge on drug particles, elasticity, bioadhesion and corneal surface retention can affect the absorption of the therapeutic element for ocular purposes. Various nanotechnology based systems have been developed for improving ocular therapeutics and increasing market demand has directed efforts for exploring commercial viability of nanotechnology based ocular systems. The nano-ocular therapeutic systems have been classified on the basis of their structures, properties and functionalities. The present review compiles elaborated information on the nano-ocular systems, their utilization, development considerations, intellectual and market aspects and the future prospects for ocular therapy.
Keywords: Nano-ocular systems, vesicular systems, colloidal systems, micelles, dendrimers, nanocomposites, carbon nanotubes, quantum dots
Call for Papers in Thematic Issues
Recent Advances in Modeling, Optimization, Characterization and Simulation of Advanced Mechanical Micro/Nano Processes
This Special Issue primarily focuses on enabling technologies that facilitate optimization, designing, Characterization, machining, and manufacturing approaches for micro/nano systems used in different domains: electrical, mechanical, thermal, magnetic, optic, fluidic. This paper collection organizes and disseminates recent research, theories, and practices relevant to areas of micro-system designing, machining, and manufacturing ...read more
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