Abstract
A growing body of epidemiologic and clinical evidence points to a significant role of biobehavioral and associated neuroendocrine factors on cancer growth and progression. This review provides an overview of the emerging relationships between neuroendocrine pathways and ovarian cancer progression. The primary focus of this review is on the contributions of neuroendocrine influences on cancer cell biology and tumor microenvironment in ovarian cancer. This mechanistic understanding will inform new opportunities for pharmacological and behavioral interventions for improving the outcome of ovarian cancer patients.
Keywords: Neuroendocrine, Ovarian cancer, Stress, Angiogenesis, Anoikis
Current Cancer Therapy Reviews
Title:Stress Related Neuroendocrine Influences in Ovarian Cancer
Volume: 8 Issue: 2
Author(s): Yu Kang, Susan K. Lutgendorf, Wei Hu, Steven W. Cole and Anil K. Sood
Affiliation:
Keywords: Neuroendocrine, Ovarian cancer, Stress, Angiogenesis, Anoikis
Abstract: A growing body of epidemiologic and clinical evidence points to a significant role of biobehavioral and associated neuroendocrine factors on cancer growth and progression. This review provides an overview of the emerging relationships between neuroendocrine pathways and ovarian cancer progression. The primary focus of this review is on the contributions of neuroendocrine influences on cancer cell biology and tumor microenvironment in ovarian cancer. This mechanistic understanding will inform new opportunities for pharmacological and behavioral interventions for improving the outcome of ovarian cancer patients.
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Kang Yu, K. Lutgendorf Susan, Hu Wei, W. Cole Steven and K. Sood Anil, Stress Related Neuroendocrine Influences in Ovarian Cancer, Current Cancer Therapy Reviews 2012; 8 (2) . https://dx.doi.org/10.2174/157339412800675315
DOI https://dx.doi.org/10.2174/157339412800675315 |
Print ISSN 1573-3947 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6301 |
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