Generic placeholder image

Current Clinical Pharmacology


ISSN (Print): 1574-8847
ISSN (Online): 2212-3938

Research Article

Awareness and Perception of Thromboembolism and Thromboprophylaxis among Hospitalized Patients in Jordan

Author(s): Anan S. Jarab*, Sayer Al-Azzam, Rawan Badaineh, Tareq L. Mukattash and Razan Bsoul

Volume 15, Issue 1, 2020

Page: [72 - 80] Pages: 9

DOI: 10.2174/1574884714666190823162055


Background and Objective: Despite the established importance of thromboprophylaxis in patients with Venous Thromboembolism (VTE), a limited number of studies have assessed the awareness of VTE and thromboprophylaxis therapy among the affected patients. The aim of the current study was to assess awareness and to explore variables associated with awareness about VTE and its thromboprophylaxis.

Methods: A cross-sectional study was conducted on hospitalized patients who received thromboprophylaxis (5000 units of heparin subcutaneously (SC) q8-12h, or 30-40 mg of enoxaparin SC once daily). In addition to the sociodemographic variables, awareness and perception of VTE and its thromboprophylaxis were assessed using a validated questionnaire. Multiple logistic regressions were conducted to build a model of variables significantly associated with VTE awareness.

Results: A total of 225 patients participated in the study, with only 38.2% and 22.2% of the participants being aware of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) respectively. Logistic regression showed that the participants with low educational level had 3.046 value, with the odds being not aware of DVT or PE compared with participants with high educational level. Participants without a personal history of VTE had 7.374 value, with the odds being not aware of DVT or PE compared with those who had a personal history of VTE. Participants who had a negative perception of VTE had 2.582 value, with the odds being not aware of DVT or PE compared with participants who had a positive perception and those who did not have any information about DVT or PE had 13.727 value, with the odds being not aware of DVT or PE.

Conclusion: The findings reveal that there is a lack of awareness about VTE and its thromboprophylaxis among the study participants. Patients with lower educational level and those with no history of previous VTE need awareness improvement about VTE and its thromboprophylaxis. Clinical Pharmacists need to focus on providing information about VTE and improving patients’ perception about VTE and its thromboprophylaxis with the aim of improving the awareness about VTE, and hence the better health outcome.

Keywords: Venous thromboembolism, thromboprophylaxis, awareness, perception, hospitalized patients, Jordan.

Graphical Abstract
Huerta C, Johansson S, Wallander MA, García Rodríguez LA. Risk factors and short-term mortality of venous thromboembolism diagnosed in the primary care setting in the United Kingdom. Arch Intern Med 2007; 167(9): 935-43.
[] [PMID: 17502535]
MacDougall DA, Boccuzzi SJ, Feliu AL, Lin J. Economic burden of deep-vein thrombosis, pulmonary embolism, and post-thrombotic syndrome. Am J Health Syst Pharm 2006; 63(20_Supplement_6): S5-S15.
Maynard GA, Morris TA, Jenkins IH, et al. Optimizing prevention of hospital-acquired venous thromboembolism (VTE): prospective validation of a VTE risk assessment model. J Hosp Med 2010; 5(1): 10-8.
[PMID: 19753640]
Heit JA. Venous Thromboembolism epidemiology: Implications for prevention and management. Semin Thromb Hemost 2002; 28(s2): 003-14.
Chisholm-Burns MA, Schwinghammer TL, Wells BG, Malone PM, DiPiro JT, Kolesar JM. Pharmacotherapy Principles and Practice. 4th ed. McGraw-Hill Education 2015.
Hill J, Treasure T. Reducing the risk of venous thromboembolism (deep vein thrombosis and pulmonary embolism) in patients admitted to hospital: summary of the NICE guideline. Heart 2010; 96(11): 879-82.
[] [PMID: 20478866]
Le Sage S, McGee M, Emed JD. Knowledge of venous thromboembolism (VTE) prevention among hospitalized patients. J Vasc Nurs 2008; 26(4): 109-17.
[] [PMID: 19022169]
Almodaimegh H, Alfehaid L, Alsuhebany N, et al. Awareness of venous thromboembolism and thromboprophylaxis among hospitalized patients: a cross-sectional study. Thromb J 2017; 15: 19.
[] [PMID: 28814942]
Wendelboe AM, McCumber M, Hylek EM, Buller H, Weitz JI, Raskob G. Global public awareness of venous thromboembolism. J Thromb Haemost 2015; 13(8): 1365-71.
[] [PMID: 26084415]
Alzoubi KH, Khassawneh BY, Obeidat B, Asfoor SS, Al-azzam SI. Awareness of patients who undergo cesarean section about venous thromboembolism prophylaxis. J Vasc Nurs 2013; 31(1): 15-20.
[] [PMID: 23481877]
Sousou T, Khorana AA. Cancer patients and awareness of venous thromboembolism. Cancer Invest 2010; 28(1): 44-5.
[] [PMID: 20001296]
Oh GJ, Moon J, Lee YM, et al. Public awareness of stroke and its predicting factors in Korea: A national public telephone survey, 2012 and 2014. J Korean Med Sci 2016; 31(11): 1703-10.
[] [PMID: 27709846]
Youness E G. Effect of educational nursing program on reducing the incidence of venous thromboembolism among postpartum women 2016; 5(4): 53-62.
Marini BL, Funk K, Kraft MD, et al. The effects of an informational video on patient knowledge, satisfaction and compliance with venous thromboembolism prophylaxis: a pilot study. Patient Educ Couns 2014; 96(2): 264-7.
[] [PMID: 24961446]

© 2024 Bentham Science Publishers | Privacy Policy