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Current Molecular Medicine


ISSN (Print): 1566-5240
ISSN (Online): 1875-5666

Lessons from HIV Movement of Macromolecules Inside the Cell

Author(s): Oliver T. Fackler, B. Matija Peterlin and Karsten Weis

Volume 1, Issue 1, 2001

Page: [1 - 7] Pages: 7

DOI: 10.2174/1566524013364167


Molecular biological investigations of HIV have made fundamental contributions to our understanding of eukaryotic biology. These studies elucidated new paradigms in transcription, RNA and protein export from the nucleus to the cytoplasm, cellular activation, morphology and vesicular trafficking.

Keywords: HIV, Macromolecules, Response TAR RNA, Trans Activation, RNA polymerase II, TATA-box Binding, Transcription TBP-Associated Factor, TFIIA, Negative Elongation factor, Major histocompatibility

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