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Current Analytical Chemistry


ISSN (Print): 1573-4110
ISSN (Online): 1875-6727

Research Article

Investigation of the Adulteration of Essential Oils by GC-MS

Author(s): Mara Dubnicka, Benjamin Cromwell and Mindy Levine*

Volume 16, Issue 8, 2020

Page: [965 - 969] Pages: 5

DOI: 10.2174/1573411015666191127093710

Price: $65


Background: A lack of regulation about the chemical composition of essential oils and the growing popularity of these oils among consumers presents an urgent need for the accurate characterization of various oil types from a variety of manufacturers. The aim of this paper was to characterize the composition of essential oils bought from a popular retail location, with the goal of understanding the chemical composition and presence of adulterants with potential toxicity.

Methods: Reported herein is an investigation into the components of a variety of essential oils using gas chromatography-mass spectrometry (GC-MS). The investigation initially focused on two popular oils, tea tree and lavender oil, and then moved to investigate four additional essential oils from the same brand (sandalwood, rose, eucalyptus, and lemongrass).

Results: Results of this analysis indicated that all six store brand essential oils contained Carbitol (in concentrations from 23% to 35%), and four of the six oils had diethyl phthalate (in concentrations ranging from 0.33% to 16%). These toxicants are particularly concerning because they are known inhalation hazards, and the intended usage of these oils is for aromatherapy (i.e. inhalation).

Conclusion: These results highlight a potentially significant and under-reported health concern from inhalation of toxic contaminants in the store brand oils, and showcase the need for more regulation and transparency about the composition of these commercial products.

Keywords: Carbitol, diethylphthalate, essential oils, GC-MS, inhalation hazards, toxicants.

Graphical Abstract
Carvalho, I.T.; Estevinho, B.N.; Santos, L. Application of microencapsulated essential oils in cosmetic and personal healthcare products - A review. Int. J. Cosmet. Sci., 2016, 38(2), 109-119.
[] [PMID: 25923295]
Goodier, M.C.; Zhang, A.J.; Nikle, A.B.; Hylwa, S.A.; Goldfarb, N.I.; Warshaw, E.M. Use of essential oils: A general population survey. Contact Dermat., 2019, 80(6), 391-393.
[] [PMID: 30548272]
Bommareddy, A.; Brozena, S.; Steigerwalt, J.; Landis, T.; Hughes, S.; Mabry, E.; Knopp, A.; VanWert, A.L.; Dwivedi, C. Medicinal properties of alpha-santalol, a naturally occurring constituent of sandalwood oil: Review Nat. Prod. Res., 2019, 33(4), 527-543.
[] [PMID: 29130352]
Peana, A.T.; D’Aquila, P.S.; Panin, F.; Serra, G.; Pippia, P.; Moretti, M.D.L. Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine, 2002, 9(8), 721-726.
[] [PMID: 12587692]
Andrade, M.A.; Braga, M.A.; Cesar, P.H.S.; Trento, M.V.C.; Espósito, M.A.; Silva, L.F.; Marcussi, S. Anticancer properties of essential oils: an overview. Curr. Cancer Drug Targets, 2018, 18(10), 957-966.
[] [PMID: 29295695]
Chohan, T.A.; Chohan, T.A.; Zhou, L.; Yang, Q.; Min, L.; Cao, H. Repellency, toxicity, gene expression profiling and in silico studies to explore insecticidal potential of Melaleuca alternifolia essential oil against Myzus persicae. Toxins (Basel), 2018, 10(11), 425.
[] [PMID: 30366370]
Nikolic, M.; Markovic, T.; Mojovic, M.; Pejin, B.; Savic, A.; Peric, T.; Markovic, D.; Stevic, T.; Sokovic, M. Chemical composition and biological activity of Gaultheria procumbens L. essential oil. Ind. Crops Prod., 2013, 49, 561-567.
Bukvički, D.; Stojković, D.; Soković, M.; Vannini, L.; Montanari, C.; Pejin, B.; Savić, A.; Veljić, M.; Grujić, S.; Marin, P.D. Satureja horvatii essential oil: in vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat. Meat Sci., 2014, 96(3), 1355-1360.
[] [PMID: 24342186]
Do, T.K.T.; Hadji-Minaglou, F.; Antoniotti, S.; Fernandez, X. Authenticity of essential oils. TrAC. Trends Analyt. Chem., 2015, 66, 146-157.
Pejin, B.; Vujisi, L.; Sabovljevic, M.; Tesevic, V.; Vajs, V. Preliminary data on essential oil composition of the moss Rhodobryum ontariense (Kindb.). Kindb. Cryptogam. Bryol., 2011, 32(2), 113-117.
Aissa, I. Znati, M.; Zardi-Bergaoui, A.; Flamini, G.; Ascrizzi, R.; Jannet, H.B.G.C. GC-MS, and NMR spectroscopy integrated analyses and in vitro antibacterial, anticholinesterase, anti-tyrosinase, and anti-5-lipoxygenase potential of Inula viscosa root fractionated essential oil. S. Afr. J. Bot., 2019, 125, 386-392.
Marriot, P.J.; Shellie, R.; Cornwell, C. Gas chromatographic technologies for the analysis of essential oils. J. Chromatogr. A, 2001, 936(1-2), 1-22.
[] [PMID: 11760992]
Abtahi, M.; Dobaradaran, S.; Torabbeigi, M.; Jorfi, S.; Gholamnia, R.; Koolivand, A.; Darabi, H.; Kavousi, A.; Saeedi, R. Health risk of phthalates in water environment: Occurrence in water resources, bottled water, and tap water, and burden of disease from exposure through drinking water in tehran. Iran. Environ. Res., 2019, 173, 469-479.
[] [PMID: 30981118]
Udden, M.M. Effects of diethylene glycol butyl ether and butoxyethoxyacetic acid on rat and human erythrocytes. Toxicol. Lett., 2005, 156(1), 95-101.
[] [PMID: 15705490]

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