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The Natural Products Journal


ISSN (Print): 2210-3155
ISSN (Online): 2210-3163

Review Article

Melatonin Could Be Beneficial in SARS-CoV-2 Therapy

Author(s): Sanaz Baghban Rahimi and Ahmad Hosseinzadeh Adli*

Volume 11, Issue 5, 2021

Published on: 05 September, 2020

Page: [600 - 608] Pages: 9

DOI: 10.2174/2210315510999200905130902

Price: $65


Novel coronavirus (SARS-CoV-2) can infect the respiratory tract and cause severe respiratory syndrome. The excessive inflammatory response is involved in the pathogenicity of the SARS-CoV-2. Symptoms of SARS-CoV-2 are generally associated with immunopathogenesis and may result in pulmonary tissue damage. Melatonin is a natural and multifunctional hormone that is involved in both physiological and pathological conditions in the body, such as immune modulation, anti-inflammation, and antioxidant. Melatonin is found in foods, animal and human milk and increases the expression of anti-inflammatory cytokines and, as an adjuvant treatment in SARS-- CoV-2 infection, it may have considerable therapeutic potential, because of its safety and immunomodulatory effects.

Keywords: Melatonin, SARS-CoV-2, treatment, anti-inflammatory, immunomodulator, natural.

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