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Current Women`s Health Reviews


ISSN (Print): 1573-4048
ISSN (Online): 1875-6581

Research Article

Advanced Maternal Age and Adverse Maternal and Neonatal Outcomes in Pregnant Women

Author(s): Reza Omani-Samani, Saman Maroufizadeh, Nafise Saedi, Nasim Shokouhi, Arezoo Esmailzadeh, Mahdi Sepidarkish, Saeid Safiri and Amir Almasi-Hashiani*

Volume 18, Issue 3, 2022

Published on: 09 October, 2020

Article ID: e111021186774 Pages: 5

DOI: 10.2174/1573404816999201009160848

Price: $65


Background: Advanced maternal age is an important predictor for maternal and neonatal outcomes such as maternal mortality, low birth weight, stillbirth, preterm birth, cesarean section and preeclampsia.

Objective: To determine the association of advanced maternal age and adverse maternal and neonatal outcomes in Iranian pregnant women.

Methods: In this hospital-based cross-sectional study, 5117 pregnant women from 103 hospitals in Tehran, Iran, participated in the study in 2015. The required data were gathered from hospitals which had the department of obstetrics and gynecology. Advanced maternal age was considered as an independent variable and unwanted pregnancy, preeclampsia, preterm birth, cesarean section and low birth weight were considered as interesting outcomes.

Results: In our study, the prevalence of advanced maternal age was 12.08%. Advanced maternal age was significantly associated with a higher risk of unwanted pregnancy (OR: 1.39, 95% CI: 1.12-1.73), preterm birth (OR: 1.75, 95% CI: 1.28-2.39) and cesarean section (OR: 1.34, 95% CI: 1.03-1.74). In our study, there was no significant relationship between advanced maternal age and preeclampsia, but this relationship could be clinically important (OR: 1.48, 95% CI: 0.99-2.20, P=0.052), and there is no significant relationship between advanced maternal age and low birth weight (OR: 1.08, 95% CI: 0.67-1.74, P=0.736).

Conclusion: Advanced maternal age is associated with a higher risk of unintended pregnancy, preterm birth and cesarean section, but our findings did not support advanced maternal age as a risk factor associated with low birth weight.

Keywords: Advanced maternal age, unwanted pregnancy, preeclampsia, premature birth, cesarean section, low birth weight, Iran.

Graphical Abstract
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