Abstract
A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events. The genetic factors underlying the importance of inheritance in atherosclerosis are starting to be understood. Genetic variation, such as mutations or common polymorphisms has been shown to be involved in modulation of a range of risk factors, such as plasma lipoprotein levels, inflammation and vascular calcification. This review presents examples of present studies of the role of genetic polymorphism in atherosclerosis.
Keywords: Atherosclerosis, genetic polymorphism, risk factors
Current Genomics
Title: Genetic Variation and Atherosclerosis
Volume: 9 Issue: 1
Author(s): Erik Biros, Mirko Karan and Jonathan Golledge
Affiliation:
Keywords: Atherosclerosis, genetic polymorphism, risk factors
Abstract: A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events. The genetic factors underlying the importance of inheritance in atherosclerosis are starting to be understood. Genetic variation, such as mutations or common polymorphisms has been shown to be involved in modulation of a range of risk factors, such as plasma lipoprotein levels, inflammation and vascular calcification. This review presents examples of present studies of the role of genetic polymorphism in atherosclerosis.
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Cite this article as:
Biros Erik, Karan Mirko and Golledge Jonathan, Genetic Variation and Atherosclerosis, Current Genomics 2008; 9 (1) . https://dx.doi.org/10.2174/138920208783884856
DOI https://dx.doi.org/10.2174/138920208783884856 |
Print ISSN 1389-2029 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5488 |
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