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Current Pharmaceutical Design

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ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

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Review Article

Overview of Polyethylene Glycol-based Materials with a Special Focus on Core-Shell Particles for Drug Delivery Application

Author(s): Nasrullah Shah*, Manzoor Hussain, Touseef Rehan, Abbas Khan and Zubair Ullah Khan

Volume 28, Issue 5, 2022

Published on: 30 November, 2021

Page: [352 - 367] Pages: 16

DOI: 10.2174/1381612827666210910104333

Price: $65

Abstract

Polyethylene glycols (PEG) are water-soluble non-ionic polymeric molecules. PEG and PEG-based materials are used for various important applications, such as solvents, adhesives, adsorbents, drug delivery agents, tissue engineering scaffolds, etc. The coating of nanoparticles with PEG forms core-shell nanoparticles. The PEG-based core-shell nanoparticles are synthesized for the development of high-quality drug delivery systems. In the present review, we first explained the basics and various applications of PEGs and PEG-based composites materials and then concentrated on the PEG-based core-shell nanoparticles for biomedical applications, specifically their use in drug delivery.

Keywords: PEGs, PEG-based composite materials, core-shell particles, applications, drug delivery applications, adhesive.

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