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Current Analytical Chemistry

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ISSN (Online): 1875-6727

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Mini-Review Article

Mini-Review on Analytical Methods Applied for Analysis and Characterization of Sericin

Author(s): Jovita Kanoujia*, Rudrakshi Dubey, Sumana Debgharia, Priyanjali Sisodia, Sabapathi Mohanalakshmi, Shvetank Bhatt, Poonam Parashar and Ankita Kishore

Volume 19, Issue 2, 2023

Published on: 05 December, 2022

Page: [119 - 129] Pages: 11

DOI: 10.2174/1573411019666221024150235

Price: $65

Abstract

Sericin is a serine-rich polydispersed glycoprotein found in Bombyx mori's cocoons. Sericin is extracted from cocoons as a protein, composed of amino acids like aspartic acid, glycine, tyrosine, serine, and glutamic acid with carboxyl, hydroxyl, and an amino group. Sericin has been explored for various pharmacological activities, such as antioxidant, anti-inflammatory, antiapoptotic, antiproliferative, antibacterial, anti-hypercholesteremia, and wound healing activity. Moreover, sericin has also been explored as a biopolymer for the preparation of nanoparticles, scaffolds, hydrogels, films, etc. This mini-review illustrates the reported methods for the characterization of extracted sericin and quantification in pharmaceutical formulations. The review covers analytical methods like UV-Visible Spectroscopy, Fouriertransform infrared spectroscopy, amino acid analysis, mass spectroscopy, and high-performance liquid chromatography with a brief explanation of every analytical method.

Keywords: Sericin, analytical method, spectroscopy, chromatography, FTIR, extraction.

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Graphical Abstract

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