A Perspective on Bone Morphogenetic Proteins: Dilemma behind Cancer- related Responses

Author(s): Anmol Kapoor and Chandi C. Mandal*

Volume 24, Issue 5, 2023

Published on: 08 March, 2023

Page: [382 - 387] Pages: 6

DOI: 10.2174/1389450124666230201144605


Bone morphogenetic proteins are a center of serious concern and are known to execute various cancer-related issues. The BMP signaling cascades have become more unpredictable as a result of their pleiotropic and risky characteristics, particularly when it comes to cancer responses. This perspective discusses the current therapeutic implications, emphasizes different cellular aspects that impact the failures of the current drug treatments, and speculates on future research avenues that include novel strategies like metabolomic studies and bio-mimetic peptide therapeutics to mitigate cancerous outcomes.

Keywords: Bone morphogenetic proteins (BMPs), cancer, dual behavior, BMP signaling, bio-mimetic peptide, signaling cascades.

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