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Current Microwave Chemistry


ISSN (Print): 2213-3356
ISSN (Online): 2213-3364

Review Article

L-Proline Catalyzed Organic Reactions via Microwave-Activation

Author(s): Rajiv Karmakar* and Chhanda Mukhopadhyay*

Volume 10, Issue 1, 2023

Published on: 14 June, 2023

Page: [26 - 42] Pages: 17

DOI: 10.2174/2213335610666230330164520

Price: $65


In the past few years, using microwave power to heat and wield chemical reactions has become a gradually more popular subject in the scientific community. Microwave-supported organic synthesis is confirmed to be involved in rapidly synthesizing novel compounds with selectivity and enhanced biological activities. Microwave flash heating for chemical synthesis is a spectacular reduction in reaction times, high yield and purity of the products, etc. A catalysis field wherein small organic molecules like L-Proline efficiently and selectively catalyzes organic transformations. Microwave-assisted L-Proline catalyzed reactions are valuable tools for making different acyclic, heterocycles, and carbocyclic scaffolds that signify the main framework of most bioactive compounds. In synthetic organic chemistry, microwave irradiation speedily discarded the conventional heating methods in the world of multicomponent and step-wise synthetic chemistry. This review discusses only L-Proline Catalyzed Organic Reactions under microwave activation using modern organic transformations, including condensation, addition, asymmetric, multi-components, and other modular reactions.

Keywords: L-Proline, Microwave-assisted synthesis, Bio-active molecules, Addition, Condensation, Cyclization reactions, Asymmetric, Multi-component reactions, and One-Pot reactions.

Graphical Abstract
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