Generic placeholder image

Current Aging Science

Editor-in-Chief

ISSN (Print): 1874-6098
ISSN (Online): 1874-6128

Research Article

Moderate Physical Activity Reduces the Odds of Sarcopenia in Community- dwelling Older Women: A Cross-sectional Study

Author(s): José Augusto Gonçalves Marini, Pedro Pugliesi Abdalla, Lucimere Bohn, Jorge Mota, Michael Duncan, André Pereira dos Santos and Dalmo Roberto Lopes Machado*

Volume 16, Issue 3, 2023

Published on: 28 April, 2023

Page: [219 - 226] Pages: 8

DOI: 10.2174/1874609816666230330171930

Price: $65

Abstract

Introduction: The time spent in different physical activity (PA) intensities is associated with sarcopenia risk for community-dwelling older women.

Aim: To evaluate the role of sitting time and physical activity (PA) level as predictors of sarcopenia odds.

Methods: In a cross-sectional study, physically independent older women (n = 67) performed the six-minute walk test to identify functional limitation (≤ 400 m). Sedentary time (as sitting time) and PA (light, moderate and vigorous) were obtained with the International Physical Activity Questionnaire (IPAQ). Sarcopenia was diagnosed as recommended by the Society of Sarcopenia, Cachexia and Wasting Disorders (SCWD). Sarcopenia odds (low muscle mass and functional limitation) was predicted by binary logistic regression, considering the weekly sitting time and PA as independent variables.

Results: Sarcopenia prevalence was 7.5% (n = 5), with functional limitation present in 38.8% (n = 26), and low muscle mass in 22.4% (n = 15). The predictive model (p = 0.014) involved moderate PA as the only significant predictor (OR = 0.999; p = 0.005; 95% CI: 0.998-1.000) of functional limitation. Moderate PA prevents sarcopenia odds. Each weekly hour of moderate PA decreased sarcopenia odds by 6%.

Conclusion: Time spent in moderate PA can prevent sarcopenia.

Keywords: Aging, anthropometry, elderly, mobility, physical activity, sedentary lifestyle.

Graphical Abstract
[1]
Morley JE, Abbatecola AM, Argiles JM, et al. Sarcopenia with limited mobility: An international consensus. J Am Med Dir Assoc 2011; 12(6): 403-9.
[http://dx.doi.org/10.1016/j.jamda.2011.04.014] [PMID: 21640657]
[2]
Anker SD, Morley JE, Haehling S. Welcome to the ICD-10 code for sarcopenia. J Cachexia Sarcopenia Muscle 2016; 7(5): 512-4.
[http://dx.doi.org/10.1002/jcsm.12147] [PMID: 27891296]
[3]
Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: Revised European consensus on definition and diagnosis. Age Ageing 2019; 48(1): 16-31.
[http://dx.doi.org/10.1093/ageing/afy169] [PMID: 30312372]
[4]
Heymsfield SB, Gonzalez MC, Lu J, Jia G, Zheng J. Skeletal muscle mass and quality: Evolution of modern measurement concepts in the context of sarcopenia. Proc Nutr Soc 2015; 74(4): 355-66.
[http://dx.doi.org/10.1017/S0029665115000129] [PMID: 25851205]
[5]
Wolinsky FD, Miller DK, Andresen EM, Malmstrom TK, Miller JP, Miller TR. Effect of subclinical status in functional limitation and disability on adverse health outcomes 3 years later. J Gerontol A Biol Sci Med Sci 2007; 62(1): 101-6.
[http://dx.doi.org/10.1093/gerona/62.1.101] [PMID: 17301046]
[6]
Antunes AC, Araújo DA, Veríssimo MT, Amaral TF. Sarcopenia and hospitalisation costs in older adults: A cross-sectional study. Nutr Diet 2017; 74(1): 46-50.
[http://dx.doi.org/10.1111/1747-0080.12287] [PMID: 28731551]
[7]
Pinedo-Villanueva R, Westbury LD, Syddall HE, et al. Health care costs associated with muscle weakness: A UK population-based estimate. Calcif Tissue Int 2019; 104(2): 137-44.
[http://dx.doi.org/10.1007/s00223-018-0478-1] [PMID: 30244338]
[8]
Diz JBM, Leopoldino AAO, Moreira BS, et al. Prevalence of sarcopenia in older Brazilians: A systematic review and meta-analysis. Geriatr Gerontol Int 2017; 17(1): 5-16.
[http://dx.doi.org/10.1111/ggi.12720] [PMID: 26799062]
[9]
Shafiee G, Keshtkar A, Soltani A, Ahadi Z, Larijani B, Heshmat R. Prevalence of sarcopenia in the world: A systematic review and meta- analysis of general population studies. J Diabetes Metab Disord 2017; 16(1): 21.
[http://dx.doi.org/10.1186/s40200-017-0302-x] [PMID: 28523252]
[10]
Pate RR, O’Neill JR, Lobelo F. The evolving definition of “sedentary”. Exerc Sport Sci Rev 2008; 36(4): 173-8.
[http://dx.doi.org/10.1097/JES.0b013e3181877d1a] [PMID: 18815485]
[11]
Leung KCW, Sum KWR, Yang YJ. Patterns of sedentary behavior among older adults in care facilities: A scoping review. Int J Environ Res Public Health 2021; 18(5): 2710.
[http://dx.doi.org/10.3390/ijerph18052710] [PMID: 33800199]
[12]
Sánchez-Sánchez JL, Mañas A, García-García FJ, et al. Sedentary behaviour, physical activity, and sarcopenia among older adults in the TSHA: Isotemporal substitution model. J Cachexia Sarcopenia Muscle 2019; 10(1): 188-98.
[http://dx.doi.org/10.1002/jcsm.12369] [PMID: 30920779]
[13]
Abdalla PP, dos Santos Carvalho A, dos Santos AP, et al. Cut-off points of knee extension strength allometrically adjusted to identify sarcopenia risk in older adults: A cross-sectional study. Arch Gerontol Geriatr 2020; 89(104100): 104100.
[http://dx.doi.org/10.1016/j.archger.2020.104100] [PMID: 32470897]
[14]
Marzetti E, Calvani R, Tosato M, et al. Physical activity and exercise as countermeasures to physical frailty and sarcopenia. Aging Clin Exp Res 2017; 29(1): 35-42.
[http://dx.doi.org/10.1007/s40520-016-0705-4] [PMID: 28181204]
[15]
Montero-Fernández N, Serra-Rexach JA. Role of exercise on sarcopenia in the elderly. Eur J Phys Rehabil Med 2013; 49(1): 131-43.
[PMID: 23575207]
[16]
Bull FC, Al-Ansari SS, Biddle S, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med 2020; 54(24): 1451-62.
[http://dx.doi.org/10.1136/bjsports-2020-102955] [PMID: 33239350]
[17]
Rosique-Esteban N, Babio N, Díaz-López A, Romaguera D, Alfredo Martínez J, Sanchez VM, et al. Leisure-time physical activity at moderate and high intensity is associated with parameters of body composition, muscle strength and sarcopenia in aged adults with obesity and metabolic syndrome from the PREDIMED-Plus study. Clinical nutrition 2019; 38(3): 1324-31.
[18]
Gianoudis J, Bailey CA, Daly RM. Associations between sedentary behaviour and body composition, muscle function and sarcopenia in community-dwelling older adults. Osteoporos is int 2015; 26(2): 571-9.
[http://dx.doi.org/10.1007/s00198-014-2895-y]
[19]
Reid N, Healy GN, Gianoudis J, Formica M, Gardiner PA, Eakin EE, et al. Association of sitting time and breaks in sitting with muscle mass, strength, function, and inflammation in community-dwelling older adults. Osteoporos is int 2018; 29(6): 1341-50.
[http://dx.doi.org/10.1007/s00198-018-4428-6]
[20]
Bolfarine H, de Oliveira Bussab W. Sampling elements. Editora Blucher 2005.
[21]
Icaza MC, Albala C. Project KNOWS. OPAS: Minimental StateExamination (MMSE) of dementia study in Chile: statistical analysis Brasília 1999; pp. 1-18.
[22]
Finney GR, Minagar A, Heilman KM. Assessment of mental status. Neurol Clin 2016; 34(1): 1-16.
[http://dx.doi.org/10.1016/j.ncl.2015.08.001] [PMID: 26613992]
[23]
Matsudo S, Araújo T, Matsudo V, Andrade D, Andrade E, Oliveira LC, et al. International Physical Activity Questionnaire (ipaq): study of validity and reproducibility in Brazil. Revista Brasileira de Atividade Física & Saúde 2012; 6(2): 5-18.
[24]
Sjostrom M, Ainsworth BE, Bauman A, Bull FC, Hamilton-Craig CR, Sallis JF. Guidelines for data processing analysis of the International Physical Activity Questionnaire (IPAQ) - Short and long forms 2005. 2005. Available from: https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwj7uuLFwNz1AhXmIbkGHYInCgYQFnoECCwQAQ&url=[https%3A%2F%2Fwww.researchgate.net%2Ffile.PostFileLoader.html%3Fid%3D5641f4c36143250eac8b45b7%26assetKey%3DAS%253A294237418606593%25401447163075131&usg=AOvVaw1VbFDU-l6YTiZL4L5OXVm_
[25]
Lohman TG, Roche AF, Martorell R. Anthropometric standardization reference manual. Human kinetics books 1988.
[26]
Venables MC, Jeukendrup AE. Physical inactivity and obesity: Links with insulin resistance and type 2 diabetes mellitus. Diabetes Metab Res Rev 2009; 25 (Suppl. 1): S18-23.
[http://dx.doi.org/10.1002/dmrr.983] [PMID: 19662619]
[27]
Aggio DA, Sartini C, Papacosta O, et al. Cross-sectional associations of objectively measured physical activity and sedentary time with sarcopenia and sarcopenic obesity in older men. Prev Med 2016; 91: 264-72.
[http://dx.doi.org/10.1016/j.ypmed.2016.08.040] [PMID: 27575317]
[28]
Chomentowski P, Dubé JJ, Amati F, et al. Moderate exercise attenuates the loss of skeletal muscle mass that occurs with intentional caloric restriction-induced weight loss in older, overweight to obese adults. J Gerontol A Biol Sci Med Sci 2009; 64A(5): 575-80.
[http://dx.doi.org/10.1093/gerona/glp007] [PMID: 19276190]
[29]
Goodpaster BH, Chomentowski P, Ward BK, Rossi A, Glynn NW, Delmonico MJ, et al. Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: A randomized controlled trial. J Appl Physiol 2008; 105(5): 1498-503.
[http://dx.doi.org/10.1152/japplphysiol.90425.2008]
[30]
Arsenault BJ, Rana JS, Lemieux I, Després JP, Kastelein JJ, Boekholdt SM, et al. Physical inactivity, abdominal obesity and risk of coronary heart disease in apparently healthy men and women. Int J Obes 2010; 34(2): 340-7.
[http://dx.doi.org/10.1038/ijo.2009.229]
[31]
Kortebein P, Symons TB, Ferrando A, et al. Functional impact of 10 days of bed rest in healthy older adults. J Gerontol A Biol Sci Med Sci 2008; 63(10): 1076-81.
[http://dx.doi.org/10.1093/gerona/63.10.1076] [PMID: 18948558]
[32]
Smith L, Tully M, Jacob L, et al. The association between sedentary behavior and sarcopenia among adults aged ≥65 Years in low- and middle-income countries. Int J Environ Res Public Health 2020; 17(5): 1708.
[http://dx.doi.org/10.3390/ijerph17051708] [PMID: 32151034]
[33]
Foong YC, Chherawala N, Aitken D, Scott D, Winzenberg T, Jones G. Accelerometer-determined physical activity, muscle mass, and leg strength in community-dwelling older adults. J Cachexia Sarcopenia Muscle 2016; 7(3): 275-83.
[http://dx.doi.org/10.1002/jcsm.12065] [PMID: 27239404]
[34]
Abdalla PP, Venturini ACR, Santos AP, et al. Normalizing calf circumference to identify low skeletal muscle mass in older women: A cross-sectional study. Nutr Hosp 2021; 38(4): 729-35.
[http://dx.doi.org/10.20960/nh.03572] [PMID: 34110225]
[35]
Rosenberg IH. Sarcopenia: Origins and clinical relevance. J Nutr 1997; 127 (Suppl. 5): 990S-1S.
[http://dx.doi.org/10.1093/jn/127.5.990S] [PMID: 9164280]
[36]
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European working group on sarcopenia in older people. Age Ageing 2010; 39(4): 412-23.
[http://dx.doi.org/10.1093/ageing/afq034] [PMID: 20392703]
[37]
Keller K, Engelhardt MJM. ligaments, journal t. Strength and muscle mass loss with aging process. Age and strength loss 2013; 3(4): 346.
[38]
Frontera WR, Hughes VA, Fielding RA, Fiatarone MA, Evans WJ, Roubenoff R. Aging of skeletal muscle: A 12-yr longitudinal study. J Appl Physiol 2000; 88(4): 1321-6.
[http://dx.doi.org/10.1152/jappl.2000.88.4.1321] [PMID: 10749826]
[39]
Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, et al. Sarcopenia: An undiagnosed condition in older adults.Current consensus definition: Prevalence, etiology, and consequences.International working group on sarcopenia. 2011; 12(4): 249-56.
[40]
Steffl M, Bohannon RW, Sontakova L, Tufano JJ, Shiells K, Holmerova I. Relationship between sarcopenia and physical activity in older people: A systematic review and meta-analysis. Clin Interv Aging 2017; 12: 835-45.
[http://dx.doi.org/10.2147/CIA.S132940] [PMID: 28553092]
[41]
Lee SY, Tung HH, Liu CY, Chen LK. Physical activity and sarcopenia in the geriatric population: A systematic review. J Am Med Dir Assoc 2018; 19(5): 378-83.
[http://dx.doi.org/10.1016/j.jamda.2018.02.003] [PMID: 29580886]
[42]
Dipietro L, Campbell WW, Buchner DM, et al. Physical activity, injurious falls, and physical function in aging: an umbrella review. Med Sci Sports Exerc 2019; 51(6): 1303-13.
[http://dx.doi.org/10.1249/MSS.0000000000001942] [PMID: 31095087]
[43]
Yen CH, Ku MH, Wang CY. Self-reported sitting time is associated with decreased mobility in older adults. J Geriatric Phys Therap 2017; 40(3): 167-73.
[http://dx.doi.org/10.1519/JPT.0000000000000092]
[44]
Takae R, Hatamoto Y, Yasukata J, et al. Association of lower-extremity muscle performance and physical activity level and intensity in middle-aged and older adults: A doubly labeled water and accelerometer study. J Nutr Health Aging 2020; 24(9): 1023-30.
[http://dx.doi.org/10.1007/s12603-020-1514-1] [PMID: 33155632]
[45]
Huang RY, Yang KC, Chang HH, Lee LT, Lu CW, Huang KC. The association between total protein and vegetable protein intake and low muscle mass among the community-dwelling elderly population in Northern Taiwan. Nutrients 2016; 8(6): 373.
[http://dx.doi.org/10.3390/nu8060373] [PMID: 27322317]
[46]
Moore DR, Churchward-Venne TA, Witard O, et al. Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men. J Gerontol A Biol Sci Med Sci 2015; 70(1): 57-62.
[http://dx.doi.org/10.1093/gerona/glu103] [PMID: 25056502]
[47]
Foong YC, Aitken D, Winzenberg T, Otahal P, Scott D, Jones G. The association between physical activity and reduced body fat lessens with age-results from a cross-sectional study in community-dwelling older adults. Exp Gerontol 2014; 55: 107-12.
[http://dx.doi.org/10.1016/j.exger.2014.04.006] [PMID: 24746512]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy