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Cardiovascular & Hematological Agents in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1871-5257
ISSN (Online): 1875-6182

Research Article

L-Tartaric Acid Inhibits Diminazene-induced Vasorelaxation in Isolated Rat Aorta

Author(s): Ayoub Amssayef, Ismail Bouadid and Mohamed Eddouks*

Volume 22, Issue 1, 2024

Published on: 10 May, 2023

Page: [83 - 89] Pages: 7

DOI: 10.2174/1871525721666230406075646

Price: $65

Abstract

Aims: The study investigated the effect of L-tartaric acid on diminazene-indiuced vasorelaxation.

Objective: This work was designed to study the effect of L-tartaric acid on diminazene-induced vasorelaxation using an ex vivo approach.

Materials and Methods: In the current investigation, the inhibitory effect of L-tartaric acid on diminazene-induced relaxation.

Results: The results confirmed that L-tartaric acid was able to inhibit in a dose-dependent manner diminazene-induced vasorelaxation.

Conclusion: This investigation provides important experimental evidence of the efficacy of Ltartaric acid in inhibiting diminazene-induced vasorelaxation.

Keywords: L-tartaric acid, ACE-2, diminazene, vasorelaxation, ex vivo, aorta ring.

Graphical Abstract
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