Generic placeholder image

Current Drug Research Reviews

Editor-in-Chief

ISSN (Print): 2589-9775
ISSN (Online): 2589-9783

Research Article

Motivational Interviewing as an Intervention to Improve Antiretroviral Treatment Initiation Among People who Inject Drugs (PWID): A Pilot Study in Jakarta and Bandung, Indonesia

Author(s): Evi Sukmaningrum, Astri Parawita Ayu*, Lydia Verina Wongso, Miasari Handayani, Sarahsita Hendrianti, Nurhayati Hamim Kawi, Nur Aini Kusmayanti, Nurjannah Sulaiman, Irwanto, Matthew Law and Rudi Wisaksana

Volume 16, Issue 2, 2024

Published on: 08 June, 2023

Page: [228 - 236] Pages: 9

DOI: 10.2174/2589977515666230531154629

open access plus

Abstract

Introduction: Progress towards the 95-95-95 target among People Who Inject Drugs (PWID) with Human Immunodeficiency Virus (HIV) infection was considerably low. A behavioral approach, such as motivational interviewing (MI), has been recognized as an effective strategy for improving HIV treatment outcomes among PWID.

Objective: This study aimed at assessing the impact of MI counselling to improve ARV initiation among HIV-positive PWID.

Methods: A cohort design pilot study was performed, and participants were recruited using a convenience sampling technique. Participants were PWID with HIV who accessed healthcare facilities in two Indonesian cities. Selected participants were assigned to an intervention group and a control group. The intervention group followed MI counselling, while the control group received ART following the standard of care. The participants were assigned to each group based on their preferences. The data was collected between January 2018 and January 2019.

Results: In total, 115 PWID with HIV participated in this study in the intervention (n = 30) and control (n = 85) groups. All but one intervention group's participants started ART, while 68/85 in the control group did so. Receiving MI counselling significantly contributed to ART initiation. In addition, the participants were followed-up until 12 months after ARV initiation. During this period, we found that similar proportions of participants in both groups discontinued the treatment, and only a small number achieved HIV viral suppression.

Conclusion: The positive effect of MI counselling on ART initiation provides insight into the possibility of its wider implementation. Further studies are needed to gain a deeper understanding of MI counselling and its effect on other outcomes of the HIV treatment cascade.

Keywords: Motivational interviewing, HIV, injecting drug use, time-to-treatment, treatment adherence, healthcare, PWID, MI counseling, ART initiation.

Graphical Abstract
[1]
In Danger: UNAIDS Global AIDS Update 2022. 2022. Available From: https://www.unaids.org/en/resources/documents/2022/in-dangerglobal-aids-update
[2]
Wolff MJ, Cortes CP, Mejìa FA, et al. Evaluating the care cascade after antiretroviral therapy initiation in Latin America. Int J STD AIDS 2018; 29(1): 4-12.
[http://dx.doi.org/10.1177/0956462417714094] [PMID: 28618980]
[3]
Rondonuwu Mr. Laporan Perkembangan HIV AIDS Dan Penyakit Infeksi Menular Seksual (PIMS) Triwulan I Tahun, 2021. Available From: https://siha.kemkes.go.id/portal/files_upload/Cover_TW_II_2020_FINAL_OK_050820_1.pdf
[4]
Januraga PP, Reekie J, Mulyani T, et al. The cascade of HIV care among key populations in Indonesia: A prospective cohort study. Lancet HIV 2018; 5(10): e560-8.
[http://dx.doi.org/10.1016/S2352-3018(18)30148-6] [PMID: 30143455]
[5]
Risher K, Mayer KH, Beyrer C. HIV treatment cascade in MSM, people who inject drugs, and sex workers. Curr Opin HIV AIDS 2015; 10(6): 420-9.
[http://dx.doi.org/10.1097/COH.0000000000000200] [PMID: 26352393]
[6]
Govindasamy D, Meghij J, Negussi EK, Baggaley RC, Ford N, Kranzer K. Interventions to improve or facilitate linkage to or retention in pre-ART (HIV) care and initiation of ART in low- and middle-income settings - a systematic review. J Int AIDS Soc 2014; 17(1): 19032.
[http://dx.doi.org/10.7448/IAS.17.1.19032] [PMID: 25095831]
[7]
Lancaster KE, Mollan KR, Hanscom BS, et al. Engaging people who inject drugs living with hiv in antiretroviral treatment and medication for opioid use disorder: Extended follow-up of HIV prevention trials network (HPTN) 074. Open Forum Infect Dis 2021; 8(8): ofab281.
[http://dx.doi.org/10.1093/ofid/ofab281] [PMID: 34458390]
[8]
Hogan A, Catley D, Goggin K, Evangeli M. Mechanisms of motivational interviewing for antiretroviral medication adherence in people with HIV. AIDS Behav 2020; 24(10): 2956-65.
[http://dx.doi.org/10.1007/s10461-020-02846-w] [PMID: 32232703]
[9]
Miller WR, Rollnick S. Motivational interviewing: Helping people change. (3rd ed.), New York: Guilford Press 2013.
[10]
Dillard PK, Zuniga JA, Holstad MM. An integrative review of the efficacy of motivational interviewing in HIV management. Patient Educ Couns 2017; 100(4): 636-46.
[11]
Hill S, Kavookjian J. Motivational interviewing as a behavioral intervention to increase HAART adherence in patients who are HIV-positive: A systematic review of the literature. AIDS Care 2012; 24(5): 583-92.
[http://dx.doi.org/10.1080/09540121.2011.630354] [PMID: 22292452]
[12]
Lawrence P, Fulbrook P, Somerset S, Schulz P. Motivational interviewing to enhance treatment attendance in mental health settings: A systematic review and meta-analysis. J Psychiatr Ment Health Nurs 2017; 24(9-10): 699-718.
[http://dx.doi.org/10.1111/jpm.12420] [PMID: 28816412]
[13]
Holstad MM, DiIorio C, Kelley ME, Resnicow K, Sharma S. Group motivational interviewing to promote adherence to antiretroviral medications and risk reduction behaviors in HIV infected women. AIDS Behav 2011; 15(5): 885-96.
[http://dx.doi.org/10.1007/s10461-010-9865-y] [PMID: 21165692]
[14]
Holstad MM, Essien JE, Ekong E, Higgins M, Teplinskiy I, Adewuyi MF. Motivational groups support adherence to antiretroviral therapy and use of risk reduction behaviors in HIV positive Nigerian women: A pilot study. Afr J Reprod Health 2012; 16(3): 14-27.
[PMID: 23437496]
[15]
Bertrand K, Roy É, Vaillancourt É, Vandermeerschen J, Berbiche D, Boivin JF. Randomized controlled trial of motivational interviewing for reducing injection risk behaviours among people who inject drugs. Addiction 2015; 110(5): 832-41.
[http://dx.doi.org/10.1111/add.12867] [PMID: 25641704]
[16]
Goggin K, Gerkovich MM, Williams KB, et al. A randomized controlled trial examining the efficacy of motivational counseling with observed therapy for antiretroviral therapy adherence. AIDS Behav 2013; 17(6): 1992-2001.
[http://dx.doi.org/10.1007/s10461-013-0467-3] [PMID: 23568228]
[17]
Vandenbroucke JP, von Elm E, Altman DG, et al. Strengthening the reporting of observational studies in epidemiology (STROBE). Epidemiology 2007; 18(6): 805-35.
[http://dx.doi.org/10.1097/EDE.0b013e3181577511] [PMID: 18049195]
[18]
STROBE 2023. Available From: https://www.strobe-statement.org/(Accessed On: 2023 Jan 26).
[19]
WHO. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. In: Global Tuberculosis Programme. (2nd ed.). WHO 2018; p. 480.
[20]
Go VF, Hershow RB, Kiriazova T, et al. Client and Provider perspectives on antiretroviral treatment uptake and adherence among people who inject drugs in Indonesia, Ukraine and Vietnam: HPTN 074. AIDS Behav 2019; 23(4): 1084-93.
[http://dx.doi.org/10.1007/s10461-018-2307-y] [PMID: 30306437]
[21]
Chakrapani V, Velayudham J, Shunmugam M, Newman PA, Dubrow R. Barriers to antiretroviral treatment access for injecting drug users living with HIV in Chennai, South India. AIDS Care 2014; 26(7): 835-41.
[http://dx.doi.org/10.1080/09540121.2013.861573] [PMID: 24283220]
[22]
Bolsewicz K, Debattista J, Vallely A, Whittaker A, Fitzgerald L. Factors associated with antiretroviral treatment uptake and adherence: A review. Perspectives from Australia, Canada, and the United Kingdom. AIDS Care 2015; 27(12): 1429-38.
[http://dx.doi.org/10.1080/09540121.2015.1114992] [PMID: 26641139]
[23]
Sued O, Cassetti I, Cecchini D, et al. Physician-delivered motivational interviewing to improve adherence and retention in care among challenging HIV-infected patients in Argentina (COPA2): Study protocol for a cluster randomized controlled trial. Trials 2018; 19(1): 396.
[http://dx.doi.org/10.1186/s13063-018-2758-5] [PMID: 30041703]
[24]
Mokhele I, Sineke T, Vujovic M, Fox MP, Ruiter RAC, Onoya D. Using intervention mapping in motivational interviewing training to improve ART uptake in Gauteng, South Africa. J Health Psychol 2020.
[PMID: 33047638]
[25]
Jake-Schoffman DE, Brown SD, Baiocchi M, et al. Methods-motivational interviewing approach for enhanced retention and attendance. Am J Prev Med 2021; 61(4): 606-17.
[http://dx.doi.org/10.1016/j.amepre.2021.04.005] [PMID: 34544560]
[26]
Bell ML. New guidance to improve sample size calculations for trials: Eliciting the target difference. Trials 2018; 19(1): 605.
[http://dx.doi.org/10.1186/s13063-018-2894-y] [PMID: 30396364]
[27]
Laporan Teknis Estimasi Jumlah Populasi Berisiko Terinfeksi HIV di Indonesia Tahun 2020.

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy