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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Research Article

Fluorescent Bodipy Sensor for Trace Detection of Nerve Agents Simulant via Supramolecular Approach

Author(s): Rossella Santonocito, Alessia Cavallaro, Roberta Puglisi, Manuelamaria Intravaia, Rosa Maria Toscano, Andrea Pappalardo and Giuseppe Trusso Sfrazzetto*

Volume 27, Issue 10, 2023

Published on: 06 September, 2023

Page: [876 - 882] Pages: 7

DOI: 10.2174/1385272827666230828121210

Abstract

The use of organophosphorus (OP) Nerve Agents (NAs) as chemical weapons still represents a real danger for the safety of population threaten by conflicts or terrorist attacks. A fast and easy-to-use detection of this hazardous gases could make the difference in emergency state. Specifically, the possibility to develop a detection system involving an easily accessible tool, such as a smartphone, is the driving force of the current research work. Due to the great advantages related to the optical sensing, we here report two new BODIPY-based fluorescent receptors for Dimethyl methyl phosphonate (DMMP) NA simulant, with one of the lowest limit of detection. A solid sensor was then developed able to give an OFF/ON response to low ppm concentration of DMMP gas, by using a common smartphone camera with an integrated open-source processing software.

Keywords: Chemical warfare agents, smartphone, supramolecular sensing, bodipy, fluorescence, sensitivity.

Graphical Abstract
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