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Mini-Reviews in Medicinal Chemistry

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ISSN (Online): 1875-5607

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Review Article

Research Progress of Tamarixetin and its Glycosides

Author(s): Cunbing Li, Mengxin Tao, Tingting Li, Xiaofen Huang*, Hong Sui* and Xueyan Fu*

Volume 24, Issue 7, 2024

Published on: 26 September, 2023

Page: [689 - 703] Pages: 15

DOI: 10.2174/1389557523666230828123425

Price: $65

Abstract

Tamarixetin and its glycosides are widely distributed in natural plants, and they are also natural flavonoid derivatives of quercetin. Its main pharmacological effects include antioxidant, antiinflammatory, antiviral, anticancer, cardiovascular effects, etc. The pharmacokinetics showed that the distribution of direct absorption differed from that of biosynthesis. At the same time, research shows that tamarixetin is safe to use because it has little self-toxicity. In this paper, 181 articles on tamarixetin published from 1976 to 2023 are obtained from PubMed, China Knowledge Base Database, Wanfang Data, and other electronic databases. Tamarixetin is searched based on keywords, and 121 articles remain. Transformation synthesis, pharmacokinetics, pharmacological action, and structureactivity relationship of tamarixetin were reviewed.

Keywords: Tamarixetin, tamarixetin glycoside, transformation synthesis, pharmacokinetics, pharmacological action, structureactivity relationship.

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