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Current Neurovascular Research

Editor-in-Chief

ISSN (Print): 1567-2026
ISSN (Online): 1875-5739

Research Article

Relationship between Body Composition and Gait Characteristics in Patients with Cerebral Small Vessel Disease

Author(s): Hongyang Xie, Zhenxi Xia, Cuiqiao Xia, Nan Zhang, Yu Ding, Hongyi Zhao and Yonghua Huang*

Volume 21, Issue 2, 2024

Published on: 28 March, 2024

Page: [205 - 213] Pages: 9

DOI: 10.2174/0115672026307602240321081657

Price: $65

Abstract

Background: This study aims to explore the correlation between body composition, encompassing factors such as muscle mass and fat distribution, and gait performance during both single-task walking (STW) and dual-task walking (DTW) in patients diagnosed with cerebral small vessel disease (CSVD).

Methods: The data of hospitalized patients diagnosed with CSVD, including cadence, stride time, velocity and stride length, as well as information on variability, asymmetry and coordination during both STW and DTW, were assessed. The number of falls reported by each participant was also assessed.

Results: A total of 95 CSVD patients were assessed, and the results showed that individuals with low appendicular skeletal muscle mass (ASM), which includes both the low ASM group and the combination of low ASM and high body fat (BF) group, had reduced velocity or cadence, shortened stride length, and prolonged stride time across all walking modalities compared to the control group. Only the combination of the low ASM and high BF group exhibited a deterioration in the coefficient of variation (CV) for all basic parameters and the Phase Coordination Index (PCI) compared to the control group across all walking patterns. Conversely, patients in the high BF group displayed a decline in basic parameters, primarily during cognitive DTW. Concurrently, the high BF group showed a significant increase in the CV and the PCI compared to the control group only during cognitive DTW. Furthermore, regardless of gender, both ASM and BF independently correlated with the occurrence of falls.

Conclusions: CSVD patients with varying body compositions could allocate different levels of attention to their daily walking routines.

Keywords: Cerebral small vessel diseases, dual-task walking, body fat, muscle mass, gait, single-task walking (STW).


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