Abstract
Genome sequences from the pufferfishes Takifugu rubripes (Fugu) and Tetraodon nigroviridis, the zebrafish Danio rerio and the medaka Oryzias latipes together with genomic data from various other fish species have opened an important era of comparative genomics shedding a new light on the structure and evolution of vertebrate genomes. For instance, comparative analysis of fish genomes has revealed that the ancestral bony vertebrate genome was composed of 12 chromosomes, has confirmed the occurrence of at least one event of genome duplication in the early history of vertebrates and has allowed the identification of conserved regulatory and coding sequences in the human genome. Importantly, major differences have been observed between teleost fish and mammalian genomes. There is now convincing evidence that all teleosts are derived from a common tetraploid fish ancestor. This tetraploidization event arose about 320-350 million years ago in the ray-finned fish lineage, followed by rediploidization and retention of hundreds of duplicate pairs. Divergent evolution of the resulting duplicates has been proposed to be involved in the species richness observed in teleost fishes. Fish genomes also contain many more families of transposable elements than mammals and birds. Finally, while the mammalian and bird lineages possess major sex determination systems with sex chromosomes conserved in very divergent species, fishes have very frequently switched between sex determination mechanisms and repeatedly created novel sex chromosomes during evolution. Hence, teleost fishes display a high level of genomic plasticity, which might be related to the astonishing biodiversity observed in these animals.
Keywords: Fish, teleost, vertebrate, evolution, genome, duplication, sex chromosome, retroelement
Current Genomics
Title: Fish Genomes, Comparative Genomics and Vertebrate Evolution
Volume: 7 Issue: 1
Author(s): A. Froschauer, I. Braasch and J.- N. Volff
Affiliation:
Keywords: Fish, teleost, vertebrate, evolution, genome, duplication, sex chromosome, retroelement
Abstract: Genome sequences from the pufferfishes Takifugu rubripes (Fugu) and Tetraodon nigroviridis, the zebrafish Danio rerio and the medaka Oryzias latipes together with genomic data from various other fish species have opened an important era of comparative genomics shedding a new light on the structure and evolution of vertebrate genomes. For instance, comparative analysis of fish genomes has revealed that the ancestral bony vertebrate genome was composed of 12 chromosomes, has confirmed the occurrence of at least one event of genome duplication in the early history of vertebrates and has allowed the identification of conserved regulatory and coding sequences in the human genome. Importantly, major differences have been observed between teleost fish and mammalian genomes. There is now convincing evidence that all teleosts are derived from a common tetraploid fish ancestor. This tetraploidization event arose about 320-350 million years ago in the ray-finned fish lineage, followed by rediploidization and retention of hundreds of duplicate pairs. Divergent evolution of the resulting duplicates has been proposed to be involved in the species richness observed in teleost fishes. Fish genomes also contain many more families of transposable elements than mammals and birds. Finally, while the mammalian and bird lineages possess major sex determination systems with sex chromosomes conserved in very divergent species, fishes have very frequently switched between sex determination mechanisms and repeatedly created novel sex chromosomes during evolution. Hence, teleost fishes display a high level of genomic plasticity, which might be related to the astonishing biodiversity observed in these animals.
Export Options
About this article
Cite this article as:
Froschauer A., Braasch I. and Volff N. J.-, Fish Genomes, Comparative Genomics and Vertebrate Evolution, Current Genomics 2006; 7 (1) . https://dx.doi.org/10.2174/138920206776389766
DOI https://dx.doi.org/10.2174/138920206776389766 |
Print ISSN 1389-2029 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5488 |
Call for Papers in Thematic Issues
Advanced AI Techniques in Big Genomic Data Analysis
The thematic issue on "Advanced AI Techniques in Big Genomic Data Analysis" aims to explore the cutting-edge methodologies and applications of artificial intelligence (AI) in the realm of genomic research, where vast amounts of data pose both challenges and opportunities. This issue will cover a broad spectrum of AI-driven strategies, ...read more
Applications of Single-cell Sequencing Technology in Reproductive Medicine
Single cell sequencing (SCS) technology utilizes individual cells' genetic material to sequence their genome, transcriptome, and epigenetics at the molecular level. It offers insights into cell heterogeneity and enables the study of limited biological materials. Since its recognition as a valuable technique in 2011, single cell sequencing has yielded numerous ...read more
Current Genomics in Cardiovascular Research
Cardiovascular diseases are the main cause of death in the world, in recent years we have had important advances in the interaction between cardiovascular disease and genomics. In this Research Topic, we intend for researchers to present their results with a focus on basic, translational and clinical investigations associated with ...read more
Deep learning in Single Cell Analysis
The field of biology is undergoing a revolution in our ability to study individual cells at the molecular level, and to integrate data from multiple sources and modalities. This has been made possible by advances in technologies for single-cell sequencing, multi-omics profiling, spatial transcriptomics, and high-throughput imaging, as well as ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Aurora B Kinase and Passenger Proteins as Targets for Cancer Therapy
Current Enzyme Inhibition Journey to the Center of the Cell: Current Nanocarrier Design Strategies Targeting Biopharmaceuticals to the Cytoplasm and Nucleus
Current Pharmaceutical Design Intracellular Signaling of the Aging Suppressor Protein Klotho
Current Molecular Medicine DNA Vaccines for Prostate Cancer
Current Cancer Therapy Reviews Molecular Targeting Agents in Renal Cell Carcinoma: Present Strategies and Future Perspectives
Current Pharmaceutical Design Liposomes and Lipid Envelope-Type Systems for Systemic siRNA Delivery
Current Pharmaceutical Design PLK1 Inhibition Radiosensitizes Breast Cancer Cells, but Shows Low Efficacy as Monotherapy or in Combination with other Cytotoxic Drugs
Anti-Cancer Agents in Medicinal Chemistry Anaesthesia in Cancer Surgery: Can it Affect Cancer Survival?
Current Clinical Pharmacology Nanocarriers for Gene Delivery - Polymer Structure, Targeting Ligands and Controlled-Release Devices
Current Nanoscience Preclinical Evidence on the Anticancer Properties of Food Peptides
Protein & Peptide Letters Cyclometalated Complexes of Platinum and Gold with Biological Properties: State-of-the-Art and Future Perspectives
Current Medicinal Chemistry Gene Therapy and Biologic Therapy with Interleukin?4
Current Gene Therapy A Molecular Link Between Diabetes and Breast Cancer: Therapeutic Potential of Repurposing Incretin-based Therapies for Breast Cancer
Current Cancer Drug Targets Effective Delivery of Male Contraceptives Behind the Blood-Testis Barrier (BTB) – Lesson from Adjudin
Current Medicinal Chemistry Reducing False Positive Findings in Statistical Analysis of Pharmacogenomic Biomarker Studies Using High-Throughput Technologies
Current Drug Safety Lopinavir Loaded Spray Dried Liposomes with Penetration Enhancers for Cytotoxic Activity
Infectious Disorders - Drug Targets Anti-Tumor Monoclonal Antibodies in Conjunction with β-Glucans: A Novel Anti- Cancer Immunotherapy
Current Medicinal Chemistry p73 as a Pharmaceutical Target for Cancer Therapy
Current Pharmaceutical Design Paeonol, a Powerful Natural Product with Broad Biological Spectra by Inhibiting Inflammatory Pathway
Current Traditional Medicine A Simple and Reliable Approach for Assessing Anticancer Activity In Vitro
Current Medicinal Chemistry