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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review in Pharmacokinetic Models on Corticosteroids

Author(s): Nabil Semmar and Nicolas Simon

Volume 6, Issue 4, 2006

Page: [417 - 428] Pages: 12

DOI: 10.2174/138955706776361420

Price: $65


The pharmacokinetics of corticosteroids provides a large set of mathematical models which led to analyse many kinetic profiles corresponding to many clinical and/or physiological situations. In this paper, we present a review on the usefulness, advantages and limits of such models which could find a large application in medicinal chemistry.

Keywords: Corticosteroids, Pharmacokinetic models, Release, Absorption, Distribution, Elimination processes

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