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Current Clinical Pharmacology


ISSN (Print): 1574-8847
ISSN (Online): 2212-3938

Determinants of Medicine-Taking in Psychiatric Patients

Author(s): Carlos Garcia-Ribera and Antoni Bulbena

Volume 6, Issue 2, 2011

Page: [100 - 107] Pages: 8

DOI: 10.2174/157488411796151156

Price: $65


Lack of adherence is a universal risk in medicine. Its consequences in terms of outcome, suffering and economic costs are immense. This is a selective review of the putative factors involved in medicine taking behavior. Adherence is multidetermined by a number of variables ranging from patient sociodemographic characteristics to factors related to patient/ psychiatrist interaction, drug tolerability and organization of care. A relevant piece of responsibility comes from the drug itself and the patient's subjective tolerability which together with the characteristics of long term treatment and insufficient insight and support result in poor or lack of adherence. The context of the patient/professional therapeutic alliance, the patient's capacities and health system availability are ultimately decisive.

Keywords: Adherence, treatment, psychopharmacology, relapse, psychosis, schizophrenia, tolerability, distress, medicine taking, haloperidol, risperidone, olanzapine

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