Abstract
Interpenetrating polymer network (IPN) based drug delivery system is basically designed to deliver drugs at a predetermined rate for a desired period of time with minimum fluctuation. Due to its physical and biological characteristics such as enhanced solubility of hydrophobic drugs, excellent swelling capacity, imparting drug stability in the formulations, biodegradability, biocompatibility, weak antigenecity and targeting of drug in a specific tissue make it suitable for drug delivery as well as biomedical applications. IPN based drug delivery is primarily used for controlled release of drugs. These systems are also used for tissue engineering such as cartilage scaffolds, bone substitutes etc. The purpose of this review article is to cover recent advances on IPN based on its utilization as drug delivery matrix system for pharmaceutical applications as well as in tissue engineering for biomedical applications. Consequently, IPN is regarded as one of the most valuable novel biomaterials.
Keywords: Interpenetrating polymer network, controlled release, biomaterial, drug delivery, tissue engineering, cartilage scaffolds, IPN BASED TABLETS, glycosaminoglycan, spectroscopy
Current Drug Therapy
Title: Pharmaceutical and Biomedical Applications of Interpenetrating Polymer Network
Volume: 6 Issue: 4
Author(s): Neelam Jain, Pramod Kumar Sharma, Arunabha Banik, Amit Gupta and Vineet Bhardwaj
Affiliation:
Keywords: Interpenetrating polymer network, controlled release, biomaterial, drug delivery, tissue engineering, cartilage scaffolds, IPN BASED TABLETS, glycosaminoglycan, spectroscopy
Abstract: Interpenetrating polymer network (IPN) based drug delivery system is basically designed to deliver drugs at a predetermined rate for a desired period of time with minimum fluctuation. Due to its physical and biological characteristics such as enhanced solubility of hydrophobic drugs, excellent swelling capacity, imparting drug stability in the formulations, biodegradability, biocompatibility, weak antigenecity and targeting of drug in a specific tissue make it suitable for drug delivery as well as biomedical applications. IPN based drug delivery is primarily used for controlled release of drugs. These systems are also used for tissue engineering such as cartilage scaffolds, bone substitutes etc. The purpose of this review article is to cover recent advances on IPN based on its utilization as drug delivery matrix system for pharmaceutical applications as well as in tissue engineering for biomedical applications. Consequently, IPN is regarded as one of the most valuable novel biomaterials.
Export Options
About this article
Cite this article as:
Jain Neelam, Kumar Sharma Pramod, Banik Arunabha, Gupta Amit and Bhardwaj Vineet, Pharmaceutical and Biomedical Applications of Interpenetrating Polymer Network, Current Drug Therapy 2011; 6 (4) . https://dx.doi.org/10.2174/157488511798109547
DOI https://dx.doi.org/10.2174/157488511798109547 |
Print ISSN 1574-8855 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3903 |
Call for Papers in Thematic Issues
Novel Therapeutic Approaches and Biomarkers for Chronic Kidney Disease (CKD)
The thematic issue on "Novel Therapeutic Approaches and Biomarkers for CKD" aims to provide a comprehensive exploration of cutting-edge strategies for the management of chronic kidney disease (CKD). This issue will delve into emerging therapeutic targets, focusing on critical aspects such as podocyte injury, endothelial dysfunction, and tubulointerstitial fibrosis, which ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Editorial [Revisiting the Paris Declaration: Pharmacogenomics and Personalized Medicine as Accelerators for Development Aid and Effectiveness]
Current Pharmacogenomics and Personalized Medicine Efficacy of PD-1 or PD-L1 Inhibitors and Central Nervous System Metastases in Advanced Cancer: A Meta-Analysis
Current Cancer Drug Targets Mouse ATP-Binding Cassette (ABC) Transporters Conferring Multi-Drug Resistance
Anti-Cancer Agents in Medicinal Chemistry Targeted Delivery for Neurodegenerative Disorders Using Gene Therapy Vectors: Gene Next Therapeutic Goals
Current Gene Therapy Biomedical Technologies for In Vitro Screening and Controlled Delivery of Neuroactive Compounds
Central Nervous System Agents in Medicinal Chemistry Pleiotropic Effects of Nitric Oxide on SARS-CoV-2 Infections
Coronaviruses Induction of Cytochrome P450 3A4 and P-Glycoprotein by the Isoxazolyl- Penicillin Antibiotic Flucloxacillin
Current Drug Metabolism Chagas Heart Disease Pathogenesis: One Mechanism or Many?
Current Molecular Medicine Morphofunctional Aspects of the Blood-Brain Barrier
Current Drug Metabolism Lantibiotic Production by Pathogenic Microorganisms
Current Protein & Peptide Science Aquaporin and Vascular Diseases
Current Neuropharmacology The Role of Adenosine in Rheumatoid Arthritis
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Central Nervous System Involvement in Pediatric Rheumatic Diseases: Current Concepts in Treatment
Current Pharmaceutical Design Nitrergic Response to Clostridium perfringens Infection in the Rat Brain Regions Effect of Red Light Irradiation
Central Nervous System Agents in Medicinal Chemistry <i>Coccidioidomycosis</i> Resulting in a Prosthetic Joint Infection in an Immunocompetent Patient after a Total Hip Arthroplasty: A Case Report and Review of the Literature
Infectious Disorders - Drug Targets MRI of Central Nervous System (CNS) Vasculitis
Current Medical Imaging Renin-Angiotensin System in Central Nervous System Diseases and its Interaction with COVID-19
Current Medicinal Chemistry Cytokine/Antibody Complexes: An Emerging Class of Immunostimulants
Current Pharmaceutical Design Can Mycobacterial Genomics Generate Novel Targets as Speed-Breakers Against the Race for Drug Resistance
Current Pharmaceutical Design Neural Stem Cells - A Promising Potential Therapy for Brain Tumors
Current Stem Cell Research & Therapy