Abstract
Granuloma, a collection of various inflammatory cells composed of lymphocytes, epithelioid cells, giant cells, mononuclear cells, eosinophils, plasma cells, and fibroblasts is a host response to an antigen(s). Specific patterns of the granulomatous response such as necrosis, caseation, and the presence or absence of microorganisms or foreign bodies aid in securing the diagnosis. The common causes of granulomatous lung disease include sarcoidosis, hypersensitivity pneumonitis, Wegeners granulomatosis, mycobacterial infections, fungal diseases, parasitic infestations, and drugs. This review, designed for practicing pulmonologists, emphasizes diagnosis and treatment of some of the common pulmonary granulomas.
Keywords: T lymphocytes, Sarcoidosis, Bronchoalveolar Lavage, Chronic beryllium disease, Tuberculosis
Current Respiratory Medicine Reviews
Title: Granulomatous Lung Disease. Disease for Pulmomologists: Diagnosis and Treatment
Volume: 3 Issue: 3
Author(s): Hidenobu Shigemitsu and Om P. Sharma
Affiliation:
Keywords: T lymphocytes, Sarcoidosis, Bronchoalveolar Lavage, Chronic beryllium disease, Tuberculosis
Abstract: Granuloma, a collection of various inflammatory cells composed of lymphocytes, epithelioid cells, giant cells, mononuclear cells, eosinophils, plasma cells, and fibroblasts is a host response to an antigen(s). Specific patterns of the granulomatous response such as necrosis, caseation, and the presence or absence of microorganisms or foreign bodies aid in securing the diagnosis. The common causes of granulomatous lung disease include sarcoidosis, hypersensitivity pneumonitis, Wegeners granulomatosis, mycobacterial infections, fungal diseases, parasitic infestations, and drugs. This review, designed for practicing pulmonologists, emphasizes diagnosis and treatment of some of the common pulmonary granulomas.
Export Options
About this article
Cite this article as:
Hidenobu Shigemitsu and Om P. Sharma , Granulomatous Lung Disease. Disease for Pulmomologists: Diagnosis and Treatment, Current Respiratory Medicine Reviews 2007; 3 (3) . https://dx.doi.org/10.2174/157339807781387535
DOI https://dx.doi.org/10.2174/157339807781387535 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Cardio-Rheumatology: Cardiovascular Complications in Systemic Autoimmune Rheumatic Diseases / Is Inflammation the Common Link and Target?
Current Vascular Pharmacology Design of New Oxazaphosphorine Anticancer Drugs
Current Pharmaceutical Design ATP Binding Cassette Transporter A1 (ABCA1) Associated Proteins:Potential Drug Targets in the Metabolic Syndrome and Atherosclerotic Disease?
Current Pharmaceutical Biotechnology The Neuroprotective Role of PEDF: Implication for the Therapy of Neurological Disorders
Current Molecular Medicine HCV-Related Rheumatic Manifestations and Therapeutic Strategies
Current Drug Targets Polymorphisms in TOLL-Like Receptor Genes and their Roles in Allergic Asthma and Atopy
Recent Patents on Inflammation & Allergy Drug Discovery Mesenchymal Stem Cells: Key Actors in Tumor Niche
Current Stem Cell Research & Therapy Transcranial Doppler Ultrasonography: Current Status
Current Medical Imaging Renal & Ocular Targets for Therapy in Wegeners Granulomatosis
Inflammation & Allergy - Drug Targets (Discontinued) Multiple Roles of the Extracellular Matrix in Inflammation
Current Pharmaceutical Design Congenital Malformations Attributed to Prenatal Exposure to Cyclophosphamide
Anti-Cancer Agents in Medicinal Chemistry Pharmacological and Clinical Basis of Treatment of Familial Mediterranean Fever (FMF) with Colchicine or Analogues: An Update
Current Drug Targets - Inflammation & Allergy The Role of Endothelin System in Cardiovascular Disease and the Potential Therapeutic Perspectives of its Inhibition
Current Topics in Medicinal Chemistry Anterior Knee Pain and Oedema-like Changes of the Suprapatellar Fat Pad: Correlation of the Symptoms with MRI Findings
Current Medical Imaging Autoimmune Diseases and Atherosclerosis: The Inflammatory Connection
Current Immunology Reviews (Discontinued) Lipid Profile of Children Suffering from Pediatric Rheumatic Diseases (pRDS)
Current Rheumatology Reviews HLA-G - From Fetal Tolerance to a Regulatory Molecule in Inflammatory Diseases
Current Immunology Reviews (Discontinued) Therapeutic Potential of Non-Coding RNAs and TLR Signalling Pathways in Rheumatoid Arthritis
Current Pharmaceutical Biotechnology Safety of Dipeptidyl Peptidase 4 Inhibitors for Treatment of Type 2 Diabetes
Current Drug Safety Rationale for Peptide and DNA Based Epitope Vaccines for Alzheimers Disease Immunotherapy
CNS & Neurological Disorders - Drug Targets