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Letters in Drug Design & Discovery


ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Design Features that Affect Psychopharmacology Trials

Author(s): Arif Khan and Kelly Schwartza

Volume 2, Issue 7, 2005

Page: [546 - 550] Pages: 5

DOI: 10.2174/157018005774479140

Price: $65


The patients psychiatric diagnoses play a large role in the design and outcome of psychopharmacology clinical trials. Among antidepressant trials, magnitude of placebo response, initial severity of depression, dosing regimen, number of treatment arms and duration of trial, choice of rating scales, and sex of the patient may influence antidepressant trial outcome.

Keywords: investigational psychopharmacological agent, Antidepressant, placebo, Clinical Trials, obsessive compulsive disorder (OCD)

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