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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Natural Products as Angiogenesis Modulators

Author(s): K. A. El Sayed

Volume 5, Issue 11, 2005

Page: [971 - 993] Pages: 23

DOI: 10.2174/138955705774575291

Price: $65

Abstract

Cancer remains one of the major causes of death worldwide. Anti-angiogenic therapy is one of the new approaches to anticancer therapy. Out of 22 angiogenesis inhibitors currently under clinical trials there are 11 natural products or were modeled on a natural product parent. This review shows the potential of natural products for the discovery of new anti-angiogenic leads.

Keywords: cancer, angiogenesis modulators, plant, marine, microbial natural products

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