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Letters in Drug Design & Discovery


ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Apoptosis Signaling Pathways as Therapeutic Targets in Lung Injury

Author(s): Kazuyoshi Kuwano, Naoki Hagimoto, Michihiro Yoshimi, Takashige Maeyama and Yoichi Nakanishi

Volume 1, Issue 3, 2004

Page: [263 - 268] Pages: 6

DOI: 10.2174/1570180043398849

Price: $65


Apoptosis plays a major role in homeostasis as well as proliferation and differentiation. The important role of epithelial and endothelial cell apoptosis in lung injury and repair has been demonstrated. Modulating signaling molecules of apoptosis may be effective treatment against lung injury.

Keywords: apoptosis, death receptor, mitochondria, necrosis, lung injury, fibrosis

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