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Current Protein & Peptide Science


ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

Synthetic Peptides in the Diagnosis of HIV Infection

Author(s): Maria Claudia Alcaro, Elisa Peroni, Paolo Rovero and Anna Maria Papini

Volume 4, Issue 4, 2003

Page: [285 - 290] Pages: 6

DOI: 10.2174/1389203033487117

Price: $65


Peptide-based enzyme-linked immunosorbent assays have been found to be enough sensitive and specific for the diagnosis of human immunodeficiency virus specific antibodies in acquired immunodeficiency syndrome patients. This review provides an overview of the most important peptides developed for use as synthetic antigens in immunodiagnosis of HIV-infected patients. In particular, many studies have been devoted to discriminate between the two retroviruses HIV-1 and HIV-2, as well as different subtypes.

Keywords: synthetic peptides, neurological diseases, commercially-available assays, prion diseases, diagnostic methodologies, autoimmune disease

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