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Current Vascular Pharmacology


ISSN (Print): 1570-1611
ISSN (Online): 1875-6212

Is Impaired Flow-Mediated Dilatation of the Brachial Artery a Cardiovascular Risk Factor?

Author(s): Stefan Agewall

Volume 1, Issue 2, 2003

Page: [107 - 109] Pages: 3

DOI: 10.2174/1570161033476745

Price: $65


Endothelial dysfunction is thought to be an important factor in the development of atherosclerosis. Over the past decade, a non-invasive technique has evolved to evaluate flow-mediated vasodilation (FMD), an endothelium-dependent function, in the brachial artery. FMD decreases with increasing age and subjects with diabetes mellitus, hypercholesterolemia, smokers and hypertension have decreased FMD. There are a few concise studies reporting that FMD predicts cardiovascular events. However, the assumption that focal measurement of brachial artery FMD predicts coronary artery disease deserves further investigation.

Keywords: flow-mediated dilatation, brachial artery, cardiovascular risk factor?, flow-mediated vasodilation, hypercholesterolemia, coronary artery disease

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